MEET PROJECT, University Residential Centre of Bertinoro (Ce.U.B), Bertinoro di Romagna, Italy
1-3 December, 2014
Arrival day: Sunday November 30
Monday, December 1 Mitochondrial Determinants of Diseases Chairman: M. Rugolo (UNIBO, Italy) 08.00 – 09.30 Registration to the course 09.30 – 10.30 E. Schon Keynote Lecture 10.30 – 11.00 Coffee Break 11.00 – 12.00 J. Montoya Mitochondrial genetic system: mutations in mitochondrial disorders 12.00 – 13.00 R. Rizzuto Mitochondrial calcium homeostasis.
13.00 – 14.30 Lunch Break 14.30 –15.30 G. Lenaers Involvement of membrane dynamics in mitochondrial physiology and pathologies. Afternoon Sessions : ESR/ER lectures Chairman: H. Prokish (TUM-MED, Germany) 15.30 – 15.50 ESR 2 S. Trifunov mtDNA deletionsaccumulation and their clonal expansion in tumorigenesis and neurodegeneration 15.50 – 16.10 ESR 5 L. Mataković Cofactor deficiency in mitochondrial diseases 16.10 – 16.30 ESR 6 M. Pezet Investigation of the mechanism underpinning the inheritance of mitochondrial DNA
16.30 – 17.00 Coffee Break
17.00 – 17.20 ESR 7 M. Giunta Modifying factors in reversible mitochondrial disease / zebrafish as a model system in RNA metabolism deficiencies
17.20 – 19.00 Poster Viewing Session
Tuesday, December 2 Mitochondria in cancer
Chairman: B. Kofler ( SALK, Austria) 09.00 – 10.00 Y. Bai The role of mitochondrial DNA mutation and mitochondrial dysfunction in tumorigenesis 10.00 – 11.00 R. Rossignol Metabolic Remodeling induced by the oncogenic HRASG12V mutation
11.00 – 11.30 Coffee Break 11.30 – 12.30 E. White Importance of autophagy in mitochondria metabolism and cancer 12.30 – 12.50 ESR 1 R. Vatrinet Targeting CI as an anticancer strategy 12.50 – 14.30 Lunch Break
Afternoon Sessions : ESR/ER lectures Chairman: I. Holt (MRC-NIMR, UK) 14.30 – 14.50 ESR 4 S. Vidali Metabolic targeting of solid cancers 14.50 – 15.10 ER 3 O. Lytovchenko Mitochondrial transport in cancer and normal cells 15.10 – 15.30 ESR 8 E. Holzerova Respiratory complexes assembly and mitochondrial lipid metabolism 15.30 – 15.50 ESR 9 L. Sanchez Caballero Structure, function and assembly defects of cI: comprehensive identification and characterization of cI chaperones 15.50 – 16.20 Coffee Break 16.20 Social activity
Wednesday, December 3
Chairman: P. Chinnery ( UNEW, UK)
Molecular strategies for diseases treatment 09.00 – 10.00 C. T. Moraes The use of mitochondrial nucleases to change mtDNA heteroplasmy
10.00 – 11.00 J. Guy Return from the darkside : the Lhon gene therapy trial
11.00 – 11.30 Coffee Break 11.30 –12.30 H. Jacobs Alternative respiratory chain enzymes: a possible therapy for mitochondrial dysfunction 12.30 – 12.50 ESR 11 E. Iannetti Automated quantitative high-content and high-throughput analysis of mitochondrial morphology and membrane potential 12.50 – 14.30 Lunch Break Afternoon Sessions : ESR/ER lectures Chairman: R. Horvath (UNEW, UK) 14.30 – 14.50 ESR 12 S. Foriel Drosophila as a model to study therapeutical approaches for mitochondrial diseases 14.50 – 15.10 ESR 13 M. Mennuni Manipulating segregation of human mitochondrial DNA
15.10 – 15.30 ER 10 U. Cagin Nuclear adaptation to mitochondrial dysfunction 15.30 – 15.50 ER 14 M. Aoun Cellular and animal models for the study of mitochondrial dysfunctions in Neurodegeneration with Brain Iron Accumulation 15.50 – 16.20 Coffee Break
16:20-16.40 P. Sant’ Antonio IMP and Mitocon Presentations 16:40-17:00 Best Posters Ceremony Conclusions and departure of outside-partnership participants
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