Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
November 6 - 12, 2013
This course presents a comprehensive overview of the theory and practice of computational methods for the identification and characterization of functional elements from DNA sequence data. The course focuses on approaches for extracting the maximum amount of information from protein and DNA sequence similarity through sequence database searches, statistical analysis, and multiple sequence alignment. TOPICS Alignment and analysis of “next-gen” sequencing data, with applications from metagenomic, RNA-Seq, and CHiP-Seq experiments The Galaxy environment for high-throughput analysis Regulatory element and motif identification from conserved signals in aligned and unaligned sequences Integration of genetic and sequence information in biological databases The ENSEMBL genome browser and BioMart
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