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The Harmful Effects of Visible Light to Skin: Gene Expression Insights

 
  July 24, 2012  
     
 
CfPA - The Center for Professional Advancement, 90 Minute Accredited Online Training
August 28, 2012 at 11:00 a.m.–12:30 p.m. (ET)


Who Should Attend
This course is intended for professionals in the cosmetics and personal care industry, sunscreens, topical pharmaceuticals and for dermatologists. It will be especially beneficial to those that specialize in:

  • Research and development 
  • Formulations 
  • Regulatory 
  • Clinical assessment

Description
This course will be available On Demand: August 29, 2012

Recent scientific evidence suggests that High Energy Visible (HEV) light is harmful to skin and a few hypotheses have been put forward describing the nature of this effect. HEV light has been shown to generate the same amount of reactive oxygen species (ROS’s) when interacting with skin as those produced by UVA and UVB combined. Yet the exact outcome of this ROS burst to biochemical cycles in skin is unknown. To add to the uncertainty, HEV light is used as a therapeutic wavelength in the clinic to alleviate skin conditions that involve high rate of cellular differentiation and proliferation such as psoriasis and acne.

This 90-minute accredited training course will discuss a multidisciplinary overview involving biochemistry, photobiology and genomics and will present for the first time the analysis of a gene expression evaluation that allows the exploration of the effect of HEV light on biochemical cascades and cell cycles. Particularly, HEV light is shown to significantly affect the attenuation of the skin’s inflammatory response and its progression to healing, barrier recovery, cell cycles and melanogenesis. Exposure of skin to HEV light generates harmful effects and may lead to suppression of healing, creation of an impaired barrier, promotion of aging through affecting cell senescence, and possibly uneven pigmentation due to premature termination of melanin synthesis.

 
 
Organized by: CfPA - The Center for Professional Advancement
Invited Speakers: Nava Dayan, Ph.D.; Skin Care Research Expert

Dr. Nava Dayan earned her Ph.D. in Pharmaceutics from the Hebrew University in Jerusalem specializing in skin delivery. She is currently an Associate Adjunct Professor in the Ernest Mario School of Pharmacy at Rutgers University, and the Research and Development and Safety Assessment Director at Lipo Chemicals Inc. During her 24 years of experience she has specialized in a variety of areas related to skin treatment:

  • The research and understanding of the interaction between topically applied compounds
    and the skin
  • Findings in skin biochemistry and especially the upper layer of the skin- the stratum 
    corneum
  • Delivery of active compounds into and through the skin and the development of delivery 
    systems to facilitate transport, improve bio-availability and reduce toxicity
  • Design and development of topically applied formulations
  • Design of clinical studies to substantiate market claims and to assure safety
  • Academic teaching and lecturing
  • Industrial experience in both development of active compounds, delivery systems and 
    finished formulations
  • Skin absorption studies in vivo and in vitro for safety/ efficacy assessment
  • In vitro methodologies for safety assessment of topically applied compounds

Dr. Dayan has received numerous awards of excellence for various papers she has authored. A technology developed by Dr. Dayan is the recipient of the Gold Award for Innovation at the 2011 In Cosmetics European Show. She is the author and co-author more than 150 publications including book chapters and was granted 8 patents. She is also the editor of the “Skin Aging Hand Book” published by Elsevier; “Innate Immunity of Skin and Oral Mucosa” Book co-edited with Prof. Philip Wertz, “Formulating Skin Care with Natural Products” Book co-edited with Dr. Lambros Kromidas; both published by Wiley and sons. Dr. Dayan is a member of the Dermatopharmaceutics Focus Group, and the Abstract Review Committee for the American Association of Pharmaceutical Scientists (AAPS). She is serves as the Educational Chair of the NYSCC Chapter and on the Scientific Advisory Board of Health Beauty America Expo and the Center for Dermal Research at the Center for Biomaterials. Dr. Dayan teaches at Rutgers University and is the Director of a variety of courses at the Center for Professional Advancement.
 
Deadline for Abstracts: n/a
 
Registration: Please click here for registration information.
E-mail: sberg@cfpa.com
 
   
 
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