Preformulation Studies for Tablet Development (2 day)

This 2 day course will consist of:

Day 1: Introduction to preformulation
Morning
. Developing a Target Product Profile
. The product development process
. What are “Preformulation studies”
. Linking material properties to formulation and processing behaviour
Afternoon
. Identifying potential Critical Product Attributes related to the drug substance
. Established techniques for materials characterisation
. Linking material properties to formulation requirements
. Atomic Force Microscopy
. ASAP—short term high stress testing for accurate shelf life assessment

Day 2: Advanced preformulation techniques
Morning
. Raman Spectroscopy and other mapping techniques
. Amorphous materials—uses and limitations
. Quantitative and Environmental XRPD
. Solid state NMR
Afternoon
. Evaluating drug substance compressibility
. Case studies, workshops
. Participants open forum and Question and Answer session.
. Practical
. Effect of crystal form and particle size on compressibility using the Gamlen Tablet Press

NOTE
Wherever possible participants should bring practical problems and examples which can be reviewed on the course. The course will be highly participative and useful for people with or without formulation experience.

Dr Michael Gamlen, Pharmaceutical Development Services - Michael is Managing Director of Pharmaceutical Development Services Ltd, a Nottingham (UK) based technical consultancy. He has over 35 years experience of tablet development.

Dr Dipankar Dey, PharmaTraining Ltd - Dipankar Dey recently joined PharmaTraining Ltd as Training Manager. A graduate of Oxford University and with a PhD from Birmingham University, he was until recently Head of Process and Validation at OYSTAR Manesty, a well known tablet equipment manufacturer.

Early-bird Fee: 21 & 22 June 2012, London UK
2 day course £1062.00 + VAT £232.40 (if applicable see VAT Notes)
if booked and paid eight weeks prior to course commencement

Full fee: 21 & 22 June 2012, London UK
2 day course £1180.00 + VAT £236.00 (if applicable see VAT Notes)