Supply Chain Management in Pharma/Biotech

Procurement

• Segmenting the portfolio
• Source planning
• Procurement cycle
• Gathering supply market intelligence
• Tendering – ITT/RFP/RFQ
• Supplier conditioning
• Supply/Service Level Agreements
• Relationship maintenance

 

Demand Supply Planning

• Current state mapping
• Envelope of uncertainty
• Demand forecasting
• Master planning
• Production scheduling
• Material Requirements Planning (MRP I)
• Manufacturing Resource Planning (MRP II)
• Capacity planning
• Sales and Operations Planning (S&OP)
• Enterprise Resource Planning (ERP) Systems

 

Inventory Management and Control

• Defining inventory policy
• Creating inventory records
• Inventory record accuracy
• Forward/reverse traceability
• Expiry/re-test dating
• Shelf life supporting stability data
• Managing excess/obsolete
• Material change control

 

Distribution Logistics

• Third party logistics providers (3PL’s)
• Modes of transport
• Incoterms (2000)
• HM Customs duty and clearance
• Commodity coding
• Channel management
• Parallel imports
• Anti-counterfeiting            

 

Continuous Improvement

• 5S
• Lean (TPS)
• Kaizen and Kaizen blitz
• Process/operational excellence
• Six sigma DMAIIC
• Single Minute Exchange of Die (SMED)
• Quality by Design (QbD)
• Process Analytical Technology (PAT)

 

Bringing it all together

• Identifying stakeholders
• Listening to Voice of the Customer (VoC)
• Defining Critical to Quality Attributes (CTQ’s)
• Creating ‘one shared view’
• Analysing the current state map
• Seeing the whole’
• Deciding architecture and reach
• Agreeing target and future states
• Developing a control plan
• Gaining organisational buy-in

Hedley Rees