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CfPA - The Center for Professional Advancement, New Brunswick, NJ
October 12-14, 2010
Who Should Attend
This course is designed for personnel in the pharmaceutical, diagnostic, biomedical engineering and biotechnology industries responsible for the specification, development and production of lyophilized products, including:
• Biochemists
• R & D Personnel
• Chemists
• Pilot Plant Operations
• Chemical Engineers
• Production Supervisors
• Microbiologists
• Managers
• Pharmacists
• QA/QC
Those new to the industry and those with previous experience will find the course beneficial. Description
This course is designed to provide participants with an up-to-date understanding of the theory and practice of lyophilization. Freeze-drying (lyophilization) will be presented and explained in physical, physicochemical, biochemical and engineering terms. Theory and practice will be interrelated and biotechnological and pharmaceutical applications will be emphasized. Participants should acquire a comprehension that transcends common disciplinary boundaries.
Topics covered will include vacuum physics, properties of water and ice, supercooling and supersaturation, phase behavior during freezing, differential thermal analysis, electrical resistance, glassy state behavior, collapse phenomena, desorption phenomena, product formulation, heat and mass transfer, development of freeze-drying cycles, end point determination, residual moisture, product stability, process scale-up, process control and optimization, Current Good Manufacturing Practice (cGMP), and validation. Fault finding and problem solving will be presented using case studies.
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Organized by:
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CfPA - The Center for Professional Advancement |
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Invited Speakers:
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Dr. J. Jeff Schwegman; Founder and CEO of AB BioTechnologies
Jeff Schwegman, Ph.D. is currently the Founder and Chief Executive Officer of AB BioTechnologies where he specializes in speaking and consulting in parenteral pre-formulation, formulation, analytical, and lyophilization of both small molecules and large biomolecules. He also holds patents and develops new technologies within the lyophilization field. Dr. Schwegman received his BS in Biochemistry from Indiana University in 1992 and began working at Cook Imaging in Bloomington Indiana, where he gained experience in analytical, formulation and process development. In 1999 he began graduate study in the Department of Industrial and Physical Pharmacy at Purdue University under the direction of Dr. Steve Nail, where his focus of research involved studying changes in the physical structure of biological molecules during lyophilization. Dr. Schwegman received his Ph.D. from Purdue University in 2003, and returned to Bloomington where he worked at Baxter Pharmaceutical Solutions as a Research Scientist in the Pharmaceutical Development group. In November 2005, he left Baxter and formed BioConvergence LLC with 3 other founders which specialized in developing new formulations and manufacturing processes for parenteral products. In February 2008, he left BioConvergence, which has become a successful company, to form AB BioTechnologies. He routinely lectures around the world on formulation, stabilization and process development of lyophilized products. He has also been an active member of AAPS since 2001.
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Deadline for Abstracts:
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n/a
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Registration:
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Please click here for registration information.
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E-mail:
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sberg@cfpa.com
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