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An Introduction to Pathways for Skin Penetration

 
  May 06, 2010  
     
 
CfPA - The Center for Professional Advancement, 90 Minute Accredited Online Training
July 20, 2010 at 11:00 a.m.–12:30 p.m. (ET)


Who Should Attend
This overview, introductory online course is intended for individuals who are interested in obtaining basic knowledge in recent findings about the skin as a barrier, possible ways of interaction between the skin and applied compounds and patterns and pathways for penetration into and through the skin. Attendees may hold a function in the following areas:

  • Skin research and development 
  • Formulation chemistry 
  • Toxicology and regulatory affairs
  • Technical sales and marketing

Description
This 90-minute accredited online training is tailored for individuals who want to gain better understanding in the detailed structure of the skin and the correlation between structure and penetration. Participants will be introduced to the biochemistry of the upper layer of the skin, the stratum corneum, and the different theories about pathways of penetration through it. The session will provide basic tools for understanding the limitations in penetration and will suggest possible ways to overcome the skin barrier. It will discuss testing models as well as considerations to be taken such as skin age and condition.

Module 1:
  • Skin structure
  • The stratum corneum
  • The living epidermis
  • The intercellular lipids
  • The role of ceramides

Module 2:
  • Gradients in the skin and their possible role in partitioning
  • The water gradient; pH gradient; lipid gradient
  • The role of pilosebaceus glands in skin penetration
  • Sebum composition; Sebum flow
  • Pore size
  • Models for pore penetration
  • The polar/pore pathway

Module 3:
  • In vitro models for skin penetration
  • In vivo models for skin penetration
  • Chemical skin permeation enhancers
  • Vesicular skin permeation enhancers

Question and Answer Session

Summary

 
 
Organized by: CfPA - The Center for Professional Advancement
Invited Speakers: Dr. Nava Dayan, Skin Care Research Expert

Dr. Nava Dayan earned her Ph.D. in Pharmaceutics from the Hebrew University in Jerusalem specializing in skin delivery. She is currently an Associate Adjunct Professor in the Ernest Mario School of Pharmacy at Rutgers University, and the R&D Director at Lipo Chemicals Inc. During her 23 years of experience she has specialized in a variety of areas related to skin treatment:

  • The research and understanding of the interaction between topically applied compounds and
    the skin
  • Findings in skin biochemistry and especially the upper layer of the skin- the stratum 
    corneum
  • Delivery of active compounds into and through the skin and the development of delivery 
    systems to facilitate transport, improve bio-availability and reduce toxicity
  • Design and development of topically applied formulations
  • Design of clinical studies to substantiate market claims and to assure safety
  • Academic teaching and lecturing
  • Industrial experience in both development of active compounds, delivery systems and 
    finished formulations
  • Skin absorption studies in vivo and in vitro for safety/ efficacy assessment
  • In vitro methodologies for safety assessment of topically applied compounds

Dr. Dayan has received numerous awards of excellence for various papers she has authored. She is the author and coauthor of more than 100 publications including book chapters and was granted 7 patents. She is also the editor of the “Skin Aging Hand Book” published by Elsevier. Dr. Dayan is a member of the Dermatopharmaceutics Focus Group, and the Abstract Review Committee for the American Association of Pharmaceutical Scientists (AAPS). She is serves as the Educational Chair of the NYSCC Chapter and on the Scientific Advisory Board of Health Beauty America Expo. Dr. Dayan teaches at Rutgers University and is the Director of a variety of courses at the Center for Professional Advancement.
 
Deadline for Abstracts: n/a
 
Registration: Please click here for registration information.
E-mail: sberg@cfpa.com
 
   
 
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