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Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory
July 27 - August 16, 2010
The Yeast Genetics & Genomics course is a modern, state of the art laboratory course designed to teach the students the full repertoire of genetic approaches needed to dissect complex problems in the yeast Saccharomyces cerevisiae. Combinations of classical genetic approaches are emphasized, including the isolation and characterization of mutants, tetrad analysis, complementation, and mitotic recombination. Molecular genetic techniques, including various types of yeast transformation, gene replacement with plasmids and PCR, construction and analysis of gene fusions, and generation of mutations in cloned genes, will also be emphasized. Students will use classical and molecular approaches to gain experience in identifying and interpreting various kinds of genetic interactions including suppression and synthetic lethality. Students will be immersed in yeast genomics and will perform and interpret experiments with DNA arrays. Students will gain first-hand experience in modern cytological approaches such as epitope tagging and imaging yeast cells using indirect immunofluorescence, GFP-protein fusions and a variety of fluorescent indicators for various subcellular organelles. Lectures on fundamental aspects of yeast genetics will be presented along with seminars given by outside speakers on topics of current interest.
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Organized by:
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Beverly Errede, Jackie Vogel, Jeffrey Smith |
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Invited Speakers:
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2010 Speakers To be Announced Last year's speakers included: Dan Burke, University of Virginia Duncan Clarke, University of Minnesota Kara Dolinski, Princeton University Gerald Fink, Whitehead Institute for Biomedical Research/MIT Thomas Fox, Cornell University Timothy Hughes, University of Toronto Maria Kilfoil, McGill University Susan Lindquist, Whitehead Institute for Biomedical Research Frank Luca, University of Pennsylvania Stephen Michnick, Universite de Montreal Jeff Smith, University of Virginia Jeremy Thorner, Univ, of Calif., Berkeley Jonathan Warner, Albert Einstein College of Medicine Virginia Zakian, Princeton University Visiting faculty will change from year to year
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Deadline for Abstracts:
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Application Deadline is March 15, 2010
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Registration:
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http://meetings.cshl.edu/course/courseapp_instr.shtml
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E-mail:
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stephens@cshl.edu
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