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The Center for Professional Advancement, 90 Minute Accredited Online Training
September 10, 2009 at 11:00 A.M. to at 11:00 a.m. - 12:30 p.m. (EST)
Who Should Attend
Professionals in the cosmetic and personal care or related industries that work and specialize in the following disciplines, as well as groups or companies that provide services in skin care in the following fields:
• Research and Development
• Regulatory Affairs
• Safety Assessment
• Product Development
• Formulations Development
Description
In the current environment of establishing regulations and environmental issues awareness, an effort is put together to offer guidance to individuals in the industry who are concerned with present approaches and future implications. With the unique position of the cosmetic and personal care industry on animal testing ban and emergence of REACH, this 90-minute accredited training is designedto present key parties involved, their positions, market leads and sources for information.
When applied to the skin and penetrates, a compound may be prone to metabolism that will convert it to an inert, more potent or toxic substance. It can also change its distribution and excretion profile. While skin metabolisms can be determined using cultured human cells, skin homogenate or microsomes or full thickness human skin, no method was officially validated. ESAC estimates that a method will not be validated before 2012. This course will review the skin as a metabolic organ, describe regulatory status and look into optional testing.
Module 1: Definitions:
• Toxicokinetics
• Skin metabolism
• Is the skin a metabolic organ?
• Passing first pass effect
Regulatory status
• ECVAM- ESAC position
• ICCVAM position
Module 2:
• Skin penetration
• Testing for systemic metabolism
Module 3: In Vitro Methods:
• Cultured human cells
• Skin homogenates or microsomes
• Full thickness human skin
Summary and future direction
Question and Answer Session
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Organized by:
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The Center for Professional Advancement |
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Invited Speakers:
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Dr. Nava Dayan, Skin Care Research Expert
Dr. Dayan earned her Ph.D. in Pharmaceutics from the Hebrew University in Jerusalem specializing in skin delivery. She is currently an Associate Adjunct Professor in the Ernest Mario School of Pharmacy at Rutgers University., and the R&D Director at Lipo Chemicals Inc. During her 22 years of experience she has specialized in a variety of areas related to skin treatment:
• The research and understanding of the interaction between topically applied
compounds and the skin.
• Findings in skin biochemistry and especially the upper layer of the skin- the stratum
corneum
• Delivery of active compounds into and through the skin and the development of delivery
systems to facilitate transport, improve bio-availability and reduce toxicity
• Design and development of topically applied formulations
• Design of clinical studies to substantiate market claims and to assure safety
• Academic teaching and lecturing
• Industrial experience in both development of active compounds, delivery systems and
finished formulations
• Skin absorption studies in vivo and in vitro for safety/ efficacy assessment
• In vitro methodologies for safety assessment of topically applied compounds
Dr. Dayan has received numerous awards of excellence for various papers she has authored. She is the author and co-author more then 100 publications including book chapters and was granted 7 patents. She is also the editor of the “Skin Aging Hand Book”. Dr. Dayan is a member of the Dermatopharmaceutics Focus Group, and the Abstract Review Committee for the American Association of Pharmaceutical Scientists (AAPS), and the Consumer Products Group of the International Controlled Release Society (CRS). She is serves on the advisory board of the NY Chapter of the Society of Cosmetic Chemists, CAAT at John Hopkins University and Health Beauty America Expo. Dr. Dayan chairs the Annual Cosmeceuticals Summit Symposium. She teaches at Rutgers University and is the Director of a variety of courses at the Center for Professional Advancement.
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Deadline for Abstracts:
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N/A
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Registration:
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Please click here for registration information.
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E-mail:
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salbers@cfpa.com
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