Royal Pharmaceutical Society of Great Britain, Cambridge
18/05/08
Morning sessions consist of advanced lectures dealing with pharmacodynamic theory, interpretation of computer output, practical experimental design, discrimination between rival models and combining data of different sources. Afternoon/evening sessions are devoted to applying the methods discussed in the lectures to actual data using WinNonlin. Three evening exercises that wrap-up each topic are also included. The course will also include a group session about moving from data to insight and building conceptual models, which has been popular with delegates in previous years. An extensive number of pharmacokinetic and pharmacodynamic models and real life data sets will be covered. Users of software other than WinNonlin would also benefit from the methods discussed in the lectures and hands-on sessions. This includes single and multiple dose dynamics, steady-state data, turnover (indirect response) models, link models, tolerance, rebound and synergistic models, bi-phasic response data, physiological kinetic/dynamic modelling, transduction models, diurnal variations, allometric models for scaling kinetic and dynamic data/parameters and antibody pkpd.
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