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The Center for Professional Advancement, Amsterdam
January 30-31, 2008
Who Should Attend
This course is designed for a broad range of personnel in the pharmaceutical industry that need a basic understanding of ADME/pharmacokinetics, especially as it pertains to drug development. It should be especially valuable for:- Those needing a basic understanding of the processes involved in absorption and disposition of drugs
- Managers of pharmacology and toxicology studies
- Scientists that direct or evaluate pre-clinical studies
- Chemists and other scientists involved in drug development
- Biomedical engineers
Description
The course will provide participants with an understanding of the principals and fundamentals for absorption, distribution, metabolism, and the elimination (ADME) of pharmaceutical chemicals. The actual dose of a drug that ultimately reaches the target tissues and exerts pharmacologic or toxicologic effects is highly dependent on the kinetics of drug absorption and disposition in the body. Many factors can influence these kinetic processes. The goal of the course is to provide training in the fundamentals of ADME that should be understood for those involved in drug development and clinical applications. The thrust of the discussions will pertain to drugs, although the concepts are appropriate for all chemical entities. Some modeling and mathematical formulations will be presented; however, the lack of mathematical background will not impede one’s ability to understand the concepts involved. Finally, a few practical examples of the ADME of drugs will be provided to illustrate how the principles are applied in real life situations.
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Organized by:
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The Center for Professional Advancement |
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Invited Speakers:
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Theodore M. Farber PH.D., DABT; ToxaChemica, International, Inc., Former FDA Director, Drug and Environmental Toxicology, Former EPA Director, Pesticide Toxicology
Dr. Theodore M. Farber, Ph.D., DABT, is a Licensed Pharmacist and Board Certified Toxicologist with over forty years experience in the testing and evaluation of pharmaceuticals, food additives, pesticides, and industrial chemicals. He has taught toxicology and pharmacology at the George Washington University, American University, U.S. Department of Agriculture, U.S. National Institute of Health, Howard University Medical School, U. of Maryland, and the American Chemical Society. He received a Ph.D. in Pharmacology from the Medical College of Virginia and a B.S. in Pharmacy from the Brooklyn College of Pharmacy. Dr. Farber served for 25 years with the U.S. FDA and US EPA and served in several important research and management positions. He represented the U.S. at OECD on testing and assessment procedures. He has authored over 75 journal articles, chapters, or books on toxicity testing and assessment.
Norbert P. Page M.S., D.V.M, DABT; ToxaChemica, International, Inc., Professor, University of Maryland
Professor Norbert Page, DVM, MS, DABT, is a Board-Certified Toxicologist with over 25 years of experience in toxicity testing and assessments, U.S. government health regulations, and environmental and public health. He received a DVM from Ohio State University and a MS in Toxicology/Radiation Biology from the U. of Rochester. He has been on the faculty of the University of Maryland (UM) since 1990, and taught Physiology and Toxicology, Environmental and Occupational Safety and Health Management, and Environmental Health. He authored the National Library of Medicine computer-assisted training in toxicology, known as ToxTutor (http://sis.nlm.nih.gov/toxtutor.cfm). Dr. Page served as Chairman of two OECD Expert Groups and a delegate to the WHO. He has authored over 100 peer reviewed scientific articles and chapters and served on the editorial boards of five toxicology and carcinogenicity journals.
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Deadline for Abstracts:
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n/a
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Registration:
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Please click here for registration information.
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E-mail:
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info@cfpa.com
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