Ist International Workshop on Molecular and Bioinformatics applications to study poli-Q diseases

9.00- 9:30 Opening.
9:30- 10:30 MSc. José Miguel Laffita Mesa, BSc. Luis E Almaguer Mederos: Molecular Biology foundations of poli-Q disesases.
10:30- 10:45 Coffe break.
10:45- 12:00 BSc. Luis E Almaguer, MSc. José Miguel Laffita Mesa: Fragment Analysis to study SCA2.
12:05- 13:30 MSc. José Miguel Laffita Mesa: Methodologies to study Somatics Mosaicisms in diseases by dynamics mutations.
13:30- 15:10 Lunch.
15:10-16:20 MSc. José Miguel Laffita Mesa: Biologicals significances of Somatics Mosaicisms in SCA2.
16:20- 17:20 MSc. José Miguel Laffita Mesa: Bioinformatics trends to study poli-Q diseases.

2nd DAY
INTRODUCTON TO BIOINFORMATICS APPLICATIONS

8:30- 9:40 MSc. José Miguel Laffita Mesa: Scientifics Bibliografies Data Bases.
 Journals, editorials,currents contents.
 Medline: Bibliografics searching: PubMed
 Others Bibliografics searchers Data Bases.
9:40- 10:30 BSc. Alfredo Valles Valdés: Moleculars Data Bases.
 European Bioinformatics Institute
 National Center for Biotechnology Information (NCBI)
 SwissProt, PIR
10:30- 10:45 Coffe break.
10:45- 12:00 BSc Erik Torres Serrano: Searching Engines.
 Sequence Retrieval System (SRS)
 Entrez (GenBank)
12:10- 13:30 BSc. Alfredo Valles Valdés: Especialized Data Bases:
 Genomics: Eucariotics, Human Genome,
 OMIM, SNIPs
 Expression, PDB, Motifs and function, Pharma
13:30- 15:10 Lunch.
15.10-16:20 B.Sc Vladimir Espinosa Angarica: Basical on structural Bioinformatic.
16.30- 18:00 B.Sc Vladimir Espinosa Angarica: Basical on sequences alignments. Gaps, matrixs, Fasta, Blast, Psi-Blast.
3rd DAY
BIOINFORMATICS APPLICATIONS TO STUDY POLI-Q DISEASES

8:30- 9:30 BSc:Vladimir Espinosa: Sequences aligments.
9:30- 10:30 Dr. Mitali Mukerjee: DNA Sequences Analysis.
 Promoter and enhancers prediction.
 SNIPs identification:
 Study of alelic substructure of SCA2 gene.
10:30- 11:00 Coffe Break.
11:00- 13:00 BSc Abel González Pérez: Value of Proteins structure.
 Helixs, beta sheets, domains, folds.
 Incoming to Data Bases: Swiss prot PDB, TrEMBL, NCBI, Entrez, EBI, SRS, PIR, PDB.
13:00- 15:00 Lunch.
15.00-16:00 B.Sc.Victor de la Torre Russis: Searching of homologues proteins using: BLAST and PSI-BLAST.
16:00- 17:00 B.Sc. Victor de la Torre Russis: JPD Use to compare proteins of the same familie: Ataxin 2 (ATX2) y Ataxin 2 related protein (A2RP).

for lodgings visit URL: http://www.ataxiacubana.sld.cu/simposio_en_lodging.htm