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FS Zollmann: HUM-MOLGEN News Alert - January 25, 2005 | ||||||||||||||||
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To: list@hum-molgen.de Subject: HUM-MOLGEN News Alert - January 25, 2005 From: FS Zollmann <zollmann@hum-molgen.de> Date: Tue, 25 Jan 2005 13:58:02 +0100 ___________________________________________________________________________ SiRNA Strategies 6-7 April 2005, Café Royal, London Effective Target Validation, In Vivo and Therapeutic Applications http://hum-molgen.org/cgi-bin/banner1/ads.pl?banner=2005-informa3 High-Level Discussion Platform for Sharing Experimental Knowledge ___________________________________________________________________________ INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS HUM-MOLGEN News Alert - January 25, 2005 - http://hum-molgen.org DIAGnostics - Clinical Research (professional requests) http://hum-molgen.org/clinical-research/ - Genetic Association Database-Expertsdb http://hum-molgen.org/bb/Forum2/HTML/000173.html - Post diagnostic request / call for collaboration http://hum-molgen.org/diagnostic-posting or contact admin@hum-molgen.org Genetic News by T.M. D'Souza, F.S. Zollmann http://hum-molgen.org/NewsGen - Call for Assistant News Editors Join our editorial team http://hum-molgen.org/NewsGen/04-2003/msg01.html - Hearing Anger In Voices Study suggests that the sound of anger enhances the brain's response to voices. http://hum-molgen.org/NewsGen/01-2005/msg33.html - Understanding Cocaine Cravings Cocaine cravings following an extended withdrawal require the activation of a protein called extracellular-signal regulated kinase (ERK) in a part of the brain involved in motivation and emotion. http://hum-molgen.org/NewsGen/01-2005/msg32.html - Tagging Strategy Makes It Easier For Researchers To Leave Their Mark New method for the quick addition of small labeling molecules promises to simplify studies tracking the localization and dynamics of cell-surface proteins without interfering with cellular function. http://hum-molgen.org/NewsGen/01-2005/msg31.html - Stem Cells In Need Of A Fresh Start Report indicates that a foreign molecule present in human embryonic stem cells (HESCs) may lead to their being killed by the immune system if they are used in a transplantation setting. http://hum-molgen.org/NewsGen/01-2005/msg30.html - Reproductive ACE A protein that controls blood pressure is also crucial for fertilization. http://hum-molgen.org/NewsGen/01-2005/msg29.html - Viagra For A Broken Heart Sildenafil, better known as Viagra, can prevent and reverse the pathological growth of the heart. http://hum-molgen.org/NewsGen/01-2005/msg28.html - Muscle-Driven Microrobots Scientists show that it is now possible to start with single cells on silicon chips and obtain micromechanical devices operated by muscle tissue. http://hum-molgen.org/NewsGen/01-2005/msg27.html - Natural Selection In Humans Report describes evidence for natural selection acting on the human genome. http://hum-molgen.org/NewsGen/01-2005/msg26.html - Stimulating Insight Into Reproductive Hormones The revelation, how follicle-stimulating hormone (FSH) binds to its receptor on the cell surface, may provide scientists with the key for aiding future drug discovery efforts. http://hum-molgen.org/NewsGen/01-2005/msg25.html - Understanding The Brain, One Cell At A Time Scientists report on a tool that can capture the activity of neuronal populations at single-cell resolution and up to four times deeper into the brain than before. http://hum-molgen.org/NewsGen/01-2005/msg24.html - Pokemon Protein Puts New Cancer Treatment On The Cards Scientists uncover the role of Pokemon, a key protein in cancer progression. http://hum-molgen.org/NewsGen/01-2005/msg23.html - Protein's Role In Immune Defence Uncovered Researchers uncover the role of a vital protein called IRF-5 in triggering immune defences against invading pathogens. http://hum-molgen.org/NewsGen/01-2005/msg22.html - Scientists Discover Key Genetic Factor in Determining HIV/AIDS Risk Individual risk of acquiring HIV and experiencing rapid disease progression is not uniform within populations http://hum-molgen.org/NewsGen/01-2005/msg21.html - Researchers simulate molecular biological clock Stochastic simulation of the mammalian circadian clock. http://hum-molgen.org/NewsGen/01-2005/msg20.html - Thinking small: Texas A&M team creates lab-on-a-chip On-chip manipulation of levitated femtodroplets http://hum-molgen.org/NewsGen/01-2005/msg19.html - Study finds more than one-third of human genome regulated by RNA Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets http://hum-molgen.org/NewsGen/01-2005/msg18.html - Found: Missing sequence of the human Y chromosome Sequence may contain genes controlling stature and tumor development http://hum-molgen.org/NewsGen/01-2005/msg17.html - COX-2 levels are elevated in smokers Tobacco smoke triggers the production of COX-2, a cellular protein linked to the development and progression of cancer http://hum-molgen.org/NewsGen/01-2005/msg16.html - Research Identifies Promising Route for Treating Age-Related Hearing Loss Proliferation of Functional Hair Cells in Vivo in the Absence of the Retinoblastoma Protein http://hum-molgen.org/NewsGen/01-2005/msg15.html - First 'atlas' of key brain genes could speed research on cancer, neurological diseases Mouse brain organization revealed through direct genome-scale TF expression analysis http://hum-molgen.org/NewsGen/01-2005/msg14.html - Transistor Genetics Self-assembled carbon-nanotube-based field-effect transistors http://hum-molgen.org/NewsGen/01-2005/msg13.html - Mouse brain tumors mimic those in human genetic disorder Natural history of neurofibromatosis 1-associated optic nerve glioma formation in mice http://hum-molgen.org/NewsGen/01-2005/msg12.html - Humans Are A 'Privileged' Evolutionary Lineage Accelerated evolution of nervous system genes in the origin of Homo sapiens http://hum-molgen.org/NewsGen/01-2005/msg11.html - Growth of common skin cancer blocked in gene-switch mice Scientists have identified genes that promote the growth and recurrence of skin cancer http://hum-molgen.org/NewsGen/01-2005/msg10.html - Contact Genetic News editors news@hum-molgen.org Literature http://hum-molgen.org/literature/ - International Journal of Biological Sciences is a new peer-reviewed journal publishing scientific papers of significance in all areas of biological sciences http://hum-molgen.org/literature/01-2005/msg01.html Biotechnical requests and sources http://hum-molgen.org/biotechnology Biomedical Positions http://hum-molgen.org/positions/ - Biochemistry / Immunology: Pre doctoral fellow University of Lleida, Lleida, 25008, Spain http://hum-molgen.org/positions/predoctoral/0522.html - Computational Genetics / Bioinformatics: Chargé de Recherche 2ème classe in Functional Genomics & Human Nutrition INRA, Saint-Genes Champanelle, 63000, France http://hum-molgen.org/positions/postdocs/2541.html - Medical Research (others): Postdoctoral Appointee (Grant Funded) UMDNJ, PISCATAWAY, 08854 http://hum-molgen.org/positions/predoctoral/0523.html - Medical Research (others): Postdoctoral Fellow UMDNJ, NEW BRUNSWICK, 08901 http://hum-molgen.org/positions/academic_positions/0186.html - Medical Research (others): Clinical Studies Manager - 290626-North Wales, PA ICON Clinical Research, Inc., NASHVILLE, 37501, USA http://hum-molgen.org/positions/non_academic_positions/1637.html - Medical Research (others): Research Teaching Specialist III (Grant Funded) UMDNJ - UNIV OF MED & DENTISTRY OF NJ, NEW BRUNSWICK, 08901 http://hum-molgen.org/positions/academic_positions/0184.html - Medical Research (others): Principal Investigator on Biomedical Engineering Shanghai Institute of Biomedical Engineering, Boston, MA 02118, USA http://hum-molgen.org/positions/academic_positions/0187.html - Medical Research (others): Research Teaching Specialist IV (Part time, Grant Funded) UMDNJ, PISCATAWAY, 08854, USA http://hum-molgen.org/positions/academic_positions/0188.html - Medical Research (others): Postdoctoral Appointee (Grant Funded) UMDNJ, NEW BRUNSWICK, 08901 http://hum-molgen.org/positions/postdocs/2543.html - Medical Research (others): Contract Associate/Analyst - North Wales, PA 290567 ICON Clinical Research, Inc., NEW BRUNSWICK, 08901 http://hum-molgen.org/positions/non_academic_positions/1639.html - Medical Research (others): Graduate Student (Grant Funded) UMDNJ, PISCATAWAY, 08854 http://hum-molgen.org/positions/academic_positions/0185.html - Medical Research (others): Medical Technologist - Johnson, AR Labcorp, Johnson, 72741 http://hum-molgen.org/positions/academic_positions/0183.html - Medical Research (others): Clinical Research Assistant - 290353 ICON Clinical Research, Inc., WILMINGTON, 19801, USA http://hum-molgen.org/positions/non_academic_positions/1640.html - Medical Research (others): Associate Director, Clinical Operations - North Wales, PA 2900052 ICON Clinical Research, Inc., North Wales, 19436, USA http://hum-molgen.org/positions/non_academic_positions/1638.html - Neurology / Neuroscience: Post doctoral position: Genetic analysis of complex lipid function in C. elegans MRC Laboratory for Molecular Cell Biology, London http://hum-molgen.org/positions/postdocs/2544.html - Others: Bio Marketing and Sales Manager Hess Associates, Toronto, Ontario, M3B 3K4, Canada http://hum-molgen.org/positions/non_academic_positions/1636.html - Pathology: Pathologist McGill University, Montreal, H3T1E1, Canada http://hum-molgen.org/positions/postdocs/2542.html - Write a position announcement (free) 1) Set up account: http://hum-molgen.de/cgi-bin/positions.pl?register 2) Post position(s): http://hum-molgen.de/cgi-bin/positions.pl?login Events in bioscience and medicine http://hum-molgen.org/meetings/ - Post event http://hum-molgen.de/cgi-bin/meetings.pl?login Registry of Biomedical Companies (954 active entries) http://hum-molgen.org/companies/ Mailing List Administration (Join or leave the list) http://hum-molgen.org/subscribe-na/ Feedback contact admin@hum-molgen.org Advertise at HUM-MOLGEN contact FS Zollmann (dialogue@hum-molgen.org) ___________________________________________________________________________ SiRNA Strategies 6-7 April 2005, Café Royal, London Effective Target Validation, In Vivo and Therapeutic Applications http://hum-molgen.org/cgi-bin/banner1/ads.pl?banner=2005-informa3 High-Level Discussion Platform for Sharing Experimental Knowledge The siRNA Strategies conference will stimulate new thoughts and ideas in the RNAi field, offering you an opportunity to hear innovative information and the latest updates. Companies who are applying RNAi will present case studies on the practical approaches and effective uses that are occurring, and are not always shared. Knowledge will be pooled and ideas investigated through focused discussion topics: • What approach to take to target validation? • Establishing the true impact of off-target effects • Unravelling the different pathways • What can delivery systems achieve? • What are the pros and cons of different chemical modification? • Addressing pharmacokinetics and modification issues for each disease • What do I need for clinical testing of an siRNA compound? ___________________________________________________________________________ -- | INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS | HUM-MOLGEN - http://hum-molgen.org | (C) 1994-2005
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