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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - February 08, 2005
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Tue, 08 Feb 2005 13:56:52 +0100

___________________________________________________________________________

SiRNA Strategies
6-7 April 2005, Café Royal, London
Effective Target Validation, In Vivo and Therapeutic Applications
http://hum-molgen.org/cgi-bin/banner1/ads.pl?banner=2005-informa3

High-Level Discussion Platform for Sharing Experimental Knowledge
___________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - February 08, 2005 - http://hum-molgen.org


DIAGnostics - Clinical Research (professional requests)
http://hum-molgen.org/clinical-research/

- Collaboration request (human genetic toxicology)
   http://hum-molgen.org/bb/Forum2/HTML/000174.html

- Post diagnostic request / call for collaboration
   http://hum-molgen.org/diagnostic-posting or
   contact admin@hum-molgen.org


Genetic News
by T.M. D'Souza, F.S. Zollmann
http://hum-molgen.org/NewsGen

- Call for Assistant News Editors
   Join our editorial team
   http://hum-molgen.org/NewsGen/04-2003/msg01.html

- International Coalition to Fund Autism Genetics Research
   An international public/private partnership of government health
   agencies and private advocacy organizations has committed more than $21
   million for research to identify the genes associated with autism
   spectrum disorders.
   http://hum-molgen.org/NewsGen/02-2005/msg18.html

- New Neurons Born In Adult Rat Cortex
   NIMH scientists have found newly born neurons that communicate via the
   chemical messenger GABA (gamma-aminobutyric acid) in adult rat cortex,
   and striatum.
   http://hum-molgen.org/NewsGen/02-2005/msg17.html

- Bone Density Appears To Recover After Adolescents Discontinue Injected
   Contraceptive
   Lower bone density appears to recover in adolescent females once they
   stop using the injected contraceptive depot medroxyprogesterone acetate
   (DMPA).
   http://hum-molgen.org/NewsGen/02-2005/msg16.html

- DNA Vaccine Banishes TB
   A new gene therapy approach could help completely eliminate the
   infection that causes one of the world's biggest killers - tuberculosis
   (TB).
   http://hum-molgen.org/NewsGen/02-2005/msg15.html

- No Longer Bird Brains
   Researchers compared parts of birds' brains with the brains of other
   animals, including mammals, and concluded that much of a bird's brain
   are responsible for carrying out advanced functions like those in
   mammals.
   http://hum-molgen.org/NewsGen/02-2005/msg14.html

- The Truth About Antidepressants And Suicide
   The current controversy over the link between antidepressants and
   suicidal behaviour in children shouldn't ignore the risks of not
   treating the disease.
   http://hum-molgen.org/NewsGen/02-2005/msg13.html

- Seeing The Forest Or The Trees
   Left- and right-handers also use different parts of the brain to focus
   on the whole versus the parts of a visual stimulus
   http://hum-molgen.org/NewsGen/02-2005/msg12.html

- New Function For Pacemaker Neurons
   Circadian pacemaker neurons transmit and modulate visual information to
   control a rapid behavioral response
   http://hum-molgen.org/NewsGen/02-2005/msg11.html

- Researchers Find New Genes Necessary To Make Embryo
   New genes with roles in the C. elegans embryo revealed using RNAi of
   ovary-enriched ORFeome clones
   http://hum-molgen.org/NewsGen/02-2005/msg10.html

- Discovery Promises Simpler Therapy For Sickle Cell Disease
   Impaired vasodilation by red blood cells in sickle cell disease
   http://hum-molgen.org/NewsGen/02-2005/msg09.html

- Viral DNA Sequence A Possible Trigger For Breast Cancer
   MMTV Env encodes an ITAM responsible for transformation of mammary
   epithelial cells
   http://hum-molgen.org/NewsGen/02-2005/msg08.html

- Search and Destroy: A New Mechanism Of Regulating RNA Degradation
   Mammalian Staufen1 Recruits Upf1 to Specific mRNA 3'UTRs so as to Elicit
   mRNA Decay
   http://hum-molgen.org/NewsGen/02-2005/msg07.html

- Protein Stops Growth Of Brain Tumor, OHSU Study Shows
   Herstatin, an autoinhibitor of the epidermal growth factor receptor
   family, blocks the intracranial growth of glioblastoma
   http://hum-molgen.org/NewsGen/02-2005/msg06.html

- Blood Test Shows Promise As Monitor For Antiangiogenic Cancer Therapy
   Genetic heterogeneity of the vasculogenic phenotype parallels
   angiogenesis
   http://hum-molgen.org/NewsGen/02-2005/msg05.html

- First U.S. Kidney Cancer Vaccine Trial Underway
   In the study, patients with stage IV renal cell carcinoma are given
   regular doses of an investigational kidney cancer vaccine, called
   Trovax, in conjunction with Interleukin-2 (IL-2).
   http://hum-molgen.org/NewsGen/02-2005/msg04.html

- New Inherited Disease Can Cause Early Aortic Rupture
   A syndrome of altered cardiovascular, craniofacial, neurocognitive and
   skeletal development caused by mutations in TGFBR1 or TGFBR2.
   http://hum-molgen.org/NewsGen/02-2005/msg03.html

- How Many Comparative Genomes Are Enough?
   A model of the statistical power of comparative genome sequence
   analysis.
   http://hum-molgen.org/NewsGen/02-2005/msg02.html

- Scientists Find Genome Structure Responsible for Gene Activation
   Genomic maps and comparative analysis of histone modifications in human
   and mouse
   http://hum-molgen.org/NewsGen/02-2005/msg01.html

- Detection of a new blood pressure-increasing hormone
   Urine adenosine tetraphosphate: a novel endothelium-derived
   vasoconstrictive factor
   http://hum-molgen.org/NewsGen/01-2005/msg34.html

- Contact Genetic News editors
   news@hum-molgen.org


Literature
http://hum-molgen.org/literature/

- New books/writing opportunities
   Lerner & Lerner is looking for scientists, researchers, and writers for
   three new English language projects
   http://hum-molgen.org/literature/01-2005/msg02.html


Biotechnical requests and sources
http://hum-molgen.org/biotechnology


Biomedical Positions
http://hum-molgen.org/positions/

- Biochemistry / Immunology: PhD student
   Charité Medical School, Berlin, 13353, Germany
   http://hum-molgen.org/positions/predoctoral/0524.html

- Biotechnology: QUALITY CONTROL SCIENTIST II - Torrance, California
   Work Wonders Staffing, LLC, USA
   http://hum-molgen.org/positions/non_academic_positions/1642.html

- Biotechnology: Bilingual Sales Representatives - Torrance, California
   Work Wonders Staffing, LLC, USA
   http://hum-molgen.org/positions/non_academic_positions/1641.html

- Cancer Research: Postdoctoral Researcher
   North West Cancer Research Fund Institute, Bangor, LL57 4SG, United
   Kingdom
   http://hum-molgen.org/positions/postdocs/2550.html

- Cell and Molecular Biology / Anatomy: POST-DOCTORAL
   INSERM, 75015 Paris France
   http://hum-molgen.org/positions/postdocs/2548.html

- Computational Genetics / Bioinformatics: PHD Position in Computational
   Biology/Bioinformatics
   International University Bremen, Bremen, 28759, Germany
   http://hum-molgen.org/positions/predoctoral/0525.html

- Computational Genetics / Bioinformatics: POST-DOCTORAL FELLOW
   International University Bremen, Bremen, 28759, Germany
   http://hum-molgen.org/positions/postdocs/2549.html

- Medical Research (others): Deputy Laboratory Manager Part Time (Grant
   Funded)
   UMDNJ, PISCATAWAY, 08854, USA
   http://hum-molgen.org/positions/academic_positions/0192.html

- Medical Research (others): Postdoctoral Appointee (Grant Funded)
   UMDNJ, PISCATAWAY, 08854, USA
   http://hum-molgen.org/positions/postdocs/2546.html

- Medical Research (others): Sr. Scientist Materials Product Development
   Clorox Company, PLEASANTON, 94566
   http://hum-molgen.org/positions/non_academic_positions/1646.html

- Medical Research (others): Research Grant Manager
   American Diabetes Association, ALEXANDRIA, 22301
   http://hum-molgen.org/positions/non_academic_positions/1643.html

- Medical Research (others): Research Teaching Specialist V Temp. Part
   time (Grant Funded)
   UMDNJ, PISCATAWAY, 08854
   http://hum-molgen.org/positions/academic_positions/0191.html

- Medical Research (others): Senior Medical Writer - GloboMax - MD or CA -
   290661
   ICON Clinical Research, Inc., SAN FRANCISCO, 94101
   http://hum-molgen.org/positions/non_academic_positions/1644.html

- Medical Research (others): Postdoctoral Appointee (Grant Funded)
   UMDNJ, PISCATAWAY, 08854, USA
   http://hum-molgen.org/positions/postdocs/2547.html

- Medical Research (others): Senior Medical Writer - GloboMax - MD or CA -
   290661
   ICON Clinical Research, Inc., HANOVER, 21076, USA
   http://hum-molgen.org/positions/non_academic_positions/1645.html

- Others: team leader in biostatistics/bioinformatics
   Public Research Center for Health, Luxembourg, L-1911, Luxembourg
   http://hum-molgen.org/positions/academic_positions/0190.html

- Others: team leader
   Public Research Center for Health, Luxembourg, L-1911, Luxembourg
   http://hum-molgen.org/positions/academic_positions/0189.html

- Physiology / Biophysics: Post-Doctoral Fellow
   Inst. of Physiology at Ludwig-Maximilians-University (LMU), Mujnich,
   80336, Germany
   http://hum-molgen.org/positions/postdocs/2545.html

- Write a position announcement (free)
   1) Set up account: http://hum-molgen.de/cgi-bin/positions.pl?register
   2) Post position(s): http://hum-molgen.de/cgi-bin/positions.pl?login


Events in bioscience and medicine
http://hum-molgen.org/meetings/

- Post event
   http://hum-molgen.de/cgi-bin/meetings.pl?login


Registry of Biomedical Companies (945 active entries)
http://hum-molgen.org/companies/


Mailing List Administration (Join or leave the list)
http://hum-molgen.org/subscribe-na/


Feedback
contact admin@hum-molgen.org


Advertise at HUM-MOLGEN
contact FS Zollmann (dialogue@hum-molgen.org)


___________________________________________________________________________

SiRNA Strategies
6-7 April 2005, Café Royal, London
Effective Target Validation, In Vivo and Therapeutic Applications
http://hum-molgen.org/cgi-bin/banner1/ads.pl?banner=2005-informa3

High-Level Discussion Platform for Sharing Experimental Knowledge

The siRNA Strategies conference will stimulate new thoughts and ideas
in the RNAi field, offering you an opportunity to hear innovative
information and the latest updates. Companies who are applying RNAi
will present case studies on the practical approaches and effective
uses that are occurring, and are not always shared.

Knowledge will be pooled and ideas investigated through focused
discussion topics:

• What approach to take to target validation?
• Establishing the true impact of off-target effects
• Unravelling the different pathways
• What can delivery systems achieve?
• What are the pros and cons of different chemical modification?
• Addressing pharmacokinetics and modification issues for each disease
• What do I need for clinical testing of an siRNA compound?

___________________________________________________________________________



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| INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
| HUM-MOLGEN - http://hum-molgen.org
| (C) 1994-2005 




   
 
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