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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - September 23, 2003
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Tue, 23 Sep 2003 11:58:55 +0200

___________________________________________________________________________

     hum-molgen: positions in bioscience and medicine
     central resource for employment in genetics and biotechnology
     => http://hum-molgen.org/positions/
___________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - September 23, 2003 - http://hum-molgen.org


DIAGnostics - Clinical Research (professional requests)
http://hum-molgen.org/clinical-research/

- Human Molecular Population Genetics
   We are working in the area of Human Molecular Population Genetics
   and are looking for International Collaborations to study the genetic
   mechanisms responsible for the susceptibility and/or resistance of certain
   common diseases like Obesity, Hypertension, Type II diabetes, CAD etc
   in specific population groups.
   http://hum-molgen.org/bb/Forum2/HTML/000155.html

- Post diagnostic request / call for collaboration
   http://hum-molgen.org/diagnostic-posting or
   contact hum-molgen@nic.surfnet.nl


Biotechnical requests and sources
http://hum-molgen.org/biotechnology

- Class A Penicillin Binding Protein Research : Gateway for a new family
   of antibiotics
   PX is seeking new financial and industrial partners to bring this
   high-potential Class A PBPs research project further along the pipeline.
   Please contact us for further information or to start exploring partnering
   options.
   http://hum-molgen.org/bb/Forum1/HTML/000109.html

- Post request or source
    http://hum-molgen.org/biotechnical-request-posting


Genetic News
by T.M. D'Souza, W. Kalle, A.W.I. Lo, R.V. Nemade, U. Sattler, F.S. Zollmann
http://hum-molgen.org/NewsGen

- How HIV Infection Kills Brain Cells
   A potent neurotoxin produced by a complex interaction of signals from
   non-neuronal brain cells may be the cause of the development of dementia
   due to the death of neurons in the brain.
   http://hum-molgen.org/NewsGen/09-2003/msg36.html

- Persistent Infection Impairs The Immune System
   Scientists have identified persistent infection as the major factor
   accounting for impaired T cell responses observed in certain infectious
   diseases, autoimmune disorders and cancers.
   http://hum-molgen.org/NewsGen/09-2003/msg35.html

- Gene Associated With Susceptibility To Common Form Of Stroke
   Scientists have identified a gene that is associated with susceptibility
   to stroke.
   http://hum-molgen.org/NewsGen/09-2003/msg34.html

- Gene Sequences Of Two Parasites That Cause Schistosomiasis
   Two groups report on the sequencing and analysis of most of the genes
   found in two of the parasites that cause schistosomiasis, a significant
   cause of morbidity and mortality in the developing world.
   http://hum-molgen.org/NewsGen/09-2003/msg33.html

- Therapeutic Cloning In Parkinsonian Mice
   In the first example of therapeutic cloning for treating a brain
   disorder, scientists have used dopamine neurons derived from cloned
   mouse embryonic stem (ES) cells to treat mice with a Parkinson-like
   condition.
   http://hum-molgen.org/NewsGen/09-2003/msg32.html

- Cell Suffocation May Cause Cancer Spread
   Starving tumour cells of oxygen may trigger their spread to other bodily
   organs.
   http://hum-molgen.org/NewsGen/09-2003/msg31.html

- Unhelpful Hedgehogs Cause Cancer
   High levels of a protein known as Sonic hedgehog (SHH) may trigger
   certain forms of digestive tract tumour.
   http://hum-molgen.org/NewsGen/09-2003/msg30.html

- Beta-blockers also control malaria infection
   Hormones that regulate cardiovascular function have been discovered to
   influence malaria infection.
   http://hum-molgen.org/NewsGen/09-2003/msg29.html

- Second-generation antisense drug reduces TNF-alpha in rheumatoid
   arthritis patients
   Isis Pharmaceuticals, Inc. announced that the final results and
   additional data analyses of this first randomized, placebo- controlled
   Phase 2a clinical trial will be presented at the 67th Annual Meeting of
   the American College of Rheumatology (ACR).
   http://hum-molgen.org/NewsGen/09-2003/msg27.html

- National Library of the Netherlands and BioMed Central agree to open
   access archive
   BioMed Central and the National Library of the Netherlands signed an
   agreement to secure the long-term digital archiving of all research
   published by BioMed Central.
   http://hum-molgen.org/NewsGen/09-2003/msg28.html

- A Cheap And Easy Way To Treat Parkinson Disease
   Infusion of D-beta-hydroxybutyrate (D-beta-HB) to mice suffering from
   Parkinson disease restored impaired brain function and protected against
   neurodegeneration and motor skill abnormalities.
   http://hum-molgen.org/NewsGen/09-2003/msg26.html

- ROMA (Representational Oligonucleotide Microarray Analysis)
   Powerful New Method Helps Reveal Genetic Basis of Cancer, Plus
   Surprising Differences in "Normal" DNA
   http://hum-molgen.org/NewsGen/09-2003/msg25.html

- Avigen Cleared to Resume Clinical Trial of Hemophilia B Treatment
   FDA, Children's Hospital of Philadelphia and Stanford University Medical
   Center Approve Resumption.
   http://hum-molgen.org/NewsGen/09-2003/msg24.html

- Merck and Alnylam Establish Industry's First Strategic Alliance to Apply
   RNA Interference for Human Therapeutics
   Merck and Alnylam will work collaboratively to advance RNAi technology
   and jointly apply the technology to develop RNAi-based therapeutics that
   selectively target human diseases.
   http://hum-molgen.org/NewsGen/09-2003/msg23.html

- Discovery Points to New Way to Control Atherosclerosis
   HHMI researchers discover a genetic switch that can dramatically reduce
   reduce fatty deposits in the coronary arteries of mice.
   http://hum-molgen.org/NewsGen/09-2003/msg22.html

- Pharmexa reports progress in US breast cancer trial
   Preliminary results with HER-2 AutoVac(TM) Protein vaccine are expected
   before the end of the year.
   http://hum-molgen.org/NewsGen/09-2003/msg21.html

- First gene therapy product to gain FDA orphan drug designation for
   pancreatic cancer
   Epeius Biotechnologies Corporation today announced that the FDA has
   approved REXIN-G, the world's first tumor-targeted injectable gene
   therapy vector, as an orphan drug for pancreatic cancer.
   http://hum-molgen.org/NewsGen/09-2003/msg20.html

- Lasker Award honors Rockefeller University biochemist for pioneering
   studies of gene activation
   Robert G. Roeder, Ph.D., a biochemist whose research has led to major
   advances in understanding how human genes are switched "on" and "off,"
   is this year's recipient of the highly prestigious Albert Lasker Award
   for Basic Medical Research.
   http://hum-molgen.org/NewsGen/09-2003/msg19.html

-  Brain cells found to hold key to growth of certain breast cancers
   The ability of some breast cancers to grow rapidly and tenaciously may
   be the result of a survival strategy borrowed from brain cells.
   http://hum-molgen.org/NewsGen/09-2003/msg18.html

- Targeting transcription: New insights into turning genes on
   Using a new approach to developing artificial transcription factors,
   Anna Mapp and coworkers have gained important insights into the workings
   of gene-activating transcription factors.
   http://hum-molgen.org/NewsGen/09-2003/msg17.html

- UCSD Researchers Identify Chromosome Location for 2nd Form of Joubert
   Syndrome
   New findings from the University of California, San Diego (UCSD) School
   of Medicine have identified chromosome 11 as a second site for a gene or
   genes that cause Joubert syndrome.
   http://hum-molgen.org/NewsGen/09-2003/msg15.html

- Contact Genetic News editors
   news@hum-molgen.org


Literature
http://hum-molgen.org/literature/

- Wilkins M et al. 2003. Experimental Therapeutics
   An introduction to a dynamic and competitive discipline.
   http://hum-molgen.org/literature/09-2003/msg02.html

- Metagene Online
   Knowledge base for inborn errors of metabolism
   http://hum-molgen.org/literature/09-2003/msg01.html


Open Topic Forum

- DNA Stuff
   http://hum-molgen.org/bb/Forum9/HTML/000048.html


Biomedical Positions
http://hum-molgen.org/positions/

- Biochemistry / Immunology: Biostatistician/Senior Biostatistician
   ICON Clinical Research, Inc., SAN FRANCISCO, 94101, USA
   http://hum-molgen.org/positions/non_academic_positions/1135.html

- Biochemistry / Immunology: Postdoctoral fellow in dendritic cell
   biology
   Faculty for clinical medicine Mannheim, University Heidelberg, 68167
   Mannheim, Germany
   http://hum-molgen.org/positions/postdocs/2293.html

- Biotechnology: Post-doctoral fellow
   Vanderbilt University, Nashville, TN 37203
   http://hum-molgen.org/positions/postdocs/2294.html

- Cardiovascular Research: PhD Student
   Department of Physiology, Justus-Liebig-University Giessen, D-35392
   Giessen, Germany
   http://hum-molgen.org/positions/predoctoral/0461.html

- Genetics: Associate Scientist III in Gene Discovery
   Randstad, BOSTON, 02101, USA
   http://hum-molgen.org/positions/non_academic_positions/1143.html

- Medical Research (others): IVRS Validation Specialist
   ICON Clinical Research, Inc., HOUSTON, 77001, USA
   http://hum-molgen.org/positions/non_academic_positions/1125.html

- Medical Research (others): IVRS Project Specialist, TX or NC
   ICON Clinical Research, Inc., HOUSTON, 77001, USA
   http://hum-molgen.org/positions/non_academic_positions/1126.html

- Medical Research (others): Business Development Associate  II,
   Proposals
   ICON Clinical Research, Inc., NORTH WALES, 19436, USA
   http://hum-molgen.org/positions/non_academic_positions/1137.html

- Medical Research (others): Data Management Project Leader
   ICON Clinical Research, Inc., NORTH WALES, 19436, USA
   http://hum-molgen.org/positions/non_academic_positions/1136.html

- Medical Research (others): Clinical Data Coordinators
   ICON Clinical Research, Inc., NORTH WALES, 19436, USA
   http://hum-molgen.org/positions/non_academic_positions/1123.html

- Medical Research (others): Clinical Research Associates
   ICON Clinical Research, Inc., TAMPA, 33601, USA
   http://hum-molgen.org/positions/non_academic_positions/1122.html

- Medical Research (others): Senior Clinical Data Coordinators
   ICON Clinical Research, Inc., NORTH WALES, 19436, USA
   http://hum-molgen.org/positions/non_academic_positions/1131.html

- Medical Research (others): IVRS Project Coordinator
   ICON Clinical Research, Inc., HOUSTON, 77001, USA
   http://hum-molgen.org/positions/non_academic_positions/1130.html

- Medical Research (others): Clinical Project Manager
   ICON Clinical Research, Inc., NORTH WALES, 19436, USA
   http://hum-molgen.org/positions/non_academic_positions/1129.html

- Medical Research (others): Clinical Research Associates
   ICON Clinical Research, Inc., Chicago, Nashville, Raleigh,
   North Wales, Tampa,  New York, San Francisco, USA
   http://hum-molgen.org/positions/non_academic_positions/1120.html
   http://hum-molgen.org/positions/non_academic_positions/1121.html
   http://hum-molgen.org/positions/non_academic_positions/1124.html
   http://hum-molgen.org/positions/non_academic_positions/1127.html
   http://hum-molgen.org/positions/non_academic_positions/1132.html
   http://hum-molgen.org/positions/non_academic_positions/1133.html
   http://hum-molgen.org/positions/non_academic_positions/1134.html

- Medical Research (others): Sr. Engineer/Research Scientist
   UTC Research Center, EAST HARTFORD, 06108, USA
   http://hum-molgen.org/positions/non_academic_positions/1140.html
   http://hum-molgen.org/positions/non_academic_positions/1141.html

- Others: ELS Specialist
   Universal Health Services, SAINT LOUIS, 63101, USA
   http://hum-molgen.org/positions/non_academic_positions/1139.html

- Others: Manager, Research Engineer
   UTC Research Center, EAST HARTFORD, 06108, USA
   http://hum-molgen.org/positions/non_academic_positions/1138.html

- Others: Associate Scientist II in Pharmacology
   Randstad, BOSTON, 02101, USA
   http://hum-molgen.org/positions/non_academic_positions/1142.html

- Others: ELS Specialist
   Universal Health Services, INDIANAPOLIS, 46201, USA
   http://hum-molgen.org/positions/postdocs/2295.html

- Write a position announcement (free)
   http://hum-molgen.org/cgi-bin/positions.pl?write0


Biomedical conferences
http://hum-molgen.org/meetings/


Registry of Biomedical Companies (1993 entries)
http://hum-molgen.org/companies/


Modify Your Profile
http://hum-molgen.org/cgi-bin/bb/ubbmisc.cgi?action=editbio


Feedback
contact HUM-MOLGEN@nic.surfnet.nl


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contact M Kurz and FS Zollmann (dialogue@hum-molgen.org)


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| (C) 1994-2003 



   
 
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