HUM-MOLGEN archive: CALL: various

Note from the editor: New CALLs! With a single E-mail you can now reach over ***3500*** colleagues from ***60*** countries world-wide, with an interest in genetics and molecular biology, for free! The CALL section is open for CALLs for collaborations, info requests (only for info which cannot obtained easily elsewhere), offers of assistance, grant deadline CALLs, CALLs for papers, etc. Occaisionally, replies will be posted at the end of this file. Please send high quality messages only, including your full name, institute and E-mail adress. Please respond to a CALL by private E-mail only, unless your reply is of interest to the entire HUM-MOLGEN community. The editor may refuse low-quality messages without further notice! Good CALLs! Arthur Bergen (owner HUM-MOLGEN) ****************************************************************************** >From bgold@ITSA.UCSF.EDUTue From: Bert Gold <bgold@ITSA.UCSF.EDU> This message was originally submitted by bgold@ITSA.UCSF.EDU to the HUM-MOLGEN list at NIC.SURFNET.NL. Netters, You may be interested in reading an article written for general audiences entitled "Trends in Human Genetics: Vital Data" on pages 100-105 of the March 1996 Scientific American by staff writer Tim Beardsley. Not only does it contain excellent photographs of Francis (Collins) sitting on his motorcycle [sorry Francis...] and Bill Haseltine looking dapper in his best combed hair and new suit [sorry Bill], but it also contains a worthwhile overview of the ELSI controversies currently surrounding the genome project. As most of you know I have rather strong opinions on most of these issues, so I will spare you my repeating my feelings here; nevertheless, I would say that this article by Beardsley is a must read for anyone who wishes to understand human genetics today, and as it is to be practiced into the future. Bert Gold, Ph.D. University of California, San Francisco School of Medicine Program in Medical Genetics PS - Bill and Francis, I think you both look very fine in the article and hope that you find my remarks (at least a little) jocular. - Bert ***************************************************************************** >From ZJVA47A@prodigy.comTue Apr 9 13:33:26 1996 Date: Wed, 06 Mar 1996 00:16:23 -0500 (EST) From: DIREC PAUL G TOMEY <ZJVA47A@prodigy.com> This message was originally submitted by ZJVA47A@PRODIGY.COM to the HMG-MOLGEN list at NIC.SURFNET.NL. My 4 yr old son demonstrates the ability to roll the tongue into the familiar "u" shape--of this I am certain. I am equally certain that neither his mom nor myself are "rollers". I understand this is impossible. His mom has cleft pallet, and received several surgical operations for this condition in early childhood. Is the cleft pallet, or surgery, or neither responsible for an inability to express this otherwise dominant trait? Or should I doubt my paternity? I would appreciate a response at your earliest convenience. Thanks so much. Paul ************************************************************************ >From WPCMJO@CARDIFF.AC.UKTue Apr 9 13:34:00 1996 Date: Fri, 08 Mar 1996 11:42:02 +0000 (GMT) From: MIKE OWEN <WPCMJO@CARDIFF.AC.UK> This message was originally submitted by WPCMJO@CARDIFF.AC.UK to the HUM-MOLGEN list at NIC.SURFNET.NL. We are interested in receiving DNA from individuals with hyperekplexia and other startle syndromes for mutation analysis of GLRA1. Sporadic as well as familial cases are of interest since we have found reccessive as well as dominant cases due to mutations in GLRA1. Mike Owen Depts. of Psychological Medicine and Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN, UK. Tel. 44 1222 743248 Fax. 44 1222 747839 email wpcmjo@cardiff.ac.uk ***************************************************************************** >From chipper@gdb.orgTue Apr 9 13:34:26 1996 Date: Fri, 08 Mar 1996 09:50:42 -0500 (EST) From: Mike Chipperfield <chipper@gdb.org> To: bergen@AMC.UVA.NL Subject: New contact information Hello, Effective Friday, March 1, I have resigned as a member of the Genome Data Base staff. I have taken a position as database consultant at Sybase Corporation, effective March 4. Please direct all future inquiries regarding GDB data submission to: data@gdb.org For those who wish to reach me personally, my new contact information is as follows: Phone: (301) 896-1102 FAX: (301) 896-1602 Email: Michael.Chipperfield@sybase.com Sincerely, Michael A. Chipperfield ************************************************************************* From: Bernd Stein <bstein@SIGNALPHARM.COM> Reply to: Human Molecular Genetics Editors <ED-MOLGEN@nic.SURFnet.nl> This message was originally submitted by bstein@SIGNALPHARM.COM to the HUM-MOLGEN list at NIC.SURFNET.NL. I am looking for information on the 1996 World Congress on Osteoporosis, Amsterdam, 18-23 May. I was unable to get information by sending a request to their Fax number. ___________________________________________________________________ Dr. Bernd Stein | Phone 619-558-7500 Signal Pharmaceuticals | FAX 619-558-7513 5555 Oberlin Drive | bstein@signalpharm.com San Diego, CA 92121 | *********************************************************************** > >You very kindly posted an announcment of a satellite meeting for QA >at the upcoming European Society for Human Genetics in London. Could >you please include the following note for the attention of relevant >subscribers to help me present some data on various national QA >systems? >Quality Assurance Schemes for Clincal Molecular Genetics: > >I've been asked to try and review various National Clinical Molecular >Genetics QC schemes in operation for the EQA meeting of 10th April. >So far >I have a limited amount of data on Australian and US schemes. I >wondered if >you were aware of any schemes running in your own country and if you >could >tell me anything about them, especially regarding the following >points: > >1. Who organises the scheme? >2. Who participates in the scheme? >3. Is the scheme recognised by Healthcare and/or Government? >4. What tests are evaluated? >5. Do you look at data interpretation and genotyping? >6. How are the results scored? >7. Is there a strategy for dealing with persistant poor performers? >8. What types of samples are distributed? >9. How is the scheme funded? >10. Are their any features you would like to include in future >schemes not >already in place? >11. Have you encountered any particular problems in administration of >the >scheme? > >thanks, >GR Taylor PhD MRCPath >Regional Clinical Molecular Genetics Lab, >St James's University Hospital, Leeds LS9 7TF >phone 113 283 7084 fax 113 267 7090 >email gtaylor@hgmp.mrc.ac.uk >http://dspace.dial.pipex.com/town/square/ai80/ *************************************************************************** >From ccmoema@EMBRATEL.NET.BRTue Apr 9 13:35:44 1996 Date: Sun, 10 Mar 1996 04:52:30 +0100 From: Audrey Ogawa <ccmoema@EMBRATEL.NET.BR> ccmoema@embratel.net.br (Audrey Ogawa) sent the following comments: ------------------------------------------------------------ Hi, I am a student of medicine and I am very interested in doing a research in the Genetics area. I am also thinking about making a fly lab with drosophila. If you can give me any help in one of these subjects, or know where I can find out more information, please, email me at ccmoema@embratel.net.br Any help you can give is a big help. Thanks for your attention. ------------------------------------------------------------ Server protocol: HTTP/1.0 Remote host: drjo014A101.embratel.net.br Remote IP address: 200.255.254.101 ************************************************************************ >From johnhands@EASYNET.CO.UKTue Apr 9 13:36:16 1996 Date: Mon, 11 Mar 1996 17:39:49 +0000 From: John Hands <johnhands@EASYNET.CO.UK> This message was originally submitted by johnhands@EASYNET.CO.UK to the HUM-MOLGEN list at NIC.SURFNET.NL. I am researching a book and would be most grateful to know of any conferences during 1996 in the USA at which developments in two areas of human molecular genetics may be announced or discussed: 1. Anti-aging treatments 2. Cancer treatments With thanks John Hands Author, UK ************************************************************************* >From leslieb@HELIX.NIH.GOVTue Apr 9 13:36:54 1996 Date: Mon, 11 Mar 1996 15:47:29 -0500 From: Leslie Biesecker <leslieb@HELIX.NIH.GOV> This message was originally submitted by leslieb@HELIX.NIH.GOV to the HUM-MOLGEN list at NIC.SURFNET.NL. I would be grateful for the Email address of Dr. J-P Fryns of Leuven, Belgium. Leslie Biesecker, MD National Institutes of Health National Center for Human Genome Research Building 49 Room 4A80 Bethesda, MD 20892-4470 Telephone: 301-402-2041 Fax: 301-402-2170 **************************************************************************** >From jptalm@DWX.COMTue Apr 9 13:37:20 1996 Date: Mon, 11 Mar 1996 23:11:32 +0100 From: Amy McKeen <jptalm@DWX.COM> To: Multiple recipients of list ED-MOLGEN <ED-MOLGEN@nic.SURFnet.nl> Subject: Call:information Resent-Date: Mon, 11 Mar 1996 23:11:32 +0100 Resent-From: owner-ed-molgen@HEARN.NIC.SURFNET.NL Resent-To: A.A.Bergen@AMC.UVA.NL jptalm@dwx.com (Amy McKeen) sent the following comments: ------------------------------------------------------------ My name is Amy McKeen. I am a junior biology major at Drake University in Des Moines, Iowa. I am doing a term paper on the debate over the genetic basis for homosexuality. If anyone could provide me with information or further resources on this topic, it would be greatly appreciated. Amy McKeen E-mail: jptalm@dwx.com ------------------------------------------------------------ Server protocol: HTTP/1.0 Remote host: sl-dwx-1-12.dsm.dwx.net Remote IP address: 198.207.231.28 **************************************************************************** >From KJKhacker1@AOL.COMTue Apr 9 13:37:51 1996 Date: Tue, 12 Mar 1996 22:44:45 -0500 From: KJKhacker1@AOL.COM This message was originally submitted by KJKhacker1@AOL.COM to the HUM-MOLGEN list at NIC.SURFNET.NL. can you tell me in as much detail as you can, how eye color is inherited. ****************************************************************************** >From MARIS@EMAIL.CHOP.EDUTue Apr 9 13:38:20 1996 Date: Thu, 14 Mar 1996 08:19:59 -0500 From: "John Maris M.D." <MARIS@EMAIL.CHOP.EDU> This message was originally submitted by MARIS@EMAIL.CHOP.EDU to the HUM-MOLGEN list at NIC.SURFNET.NL. We are interested in the molecular genetics of familial neuroblastoma and have an IRB approved protocol for specimen procurement and linkage analysis. We would appreciate being notified of any patients/families that meet any of the following criteria and whom might be interested in providing a blood sample (archival tumor specimens useful also): 1. Proband with one or more first degree relative with neuroblastoma, ganglioneuroblastoma or ganglioneuroma. 2. Proband affected with and/or with one or more first degree relative with Hirschsprung disease or hypoventilation syndrome. 3. Neuroblastoma patients with any other co-morbid condition (congenital malformations, mental retardation, etc.). We will be happy to provide additional information. Furthermore, we will send copies of consent and specimen procurement forms at your request. Thank you. John M. Maris, MD The Children's Hospital of Philadelphia fax: 215-590-3770 voice: 215 590-5242 email: maris@email.chop.edu *************************************************************************** >From hsiao@MAIL.PMF.ORG.TWTue Apr 9 13:41:00 1996 Date: Mon, 18 Mar 1996 07:30:59 +0100 From: "Kwang-Jen Hsiao, Ph.D." <hsiao@MAIL.PMF.ORG.TW> hsiao@mail.pmf.org.tw (Kwang-Jen Hsiao, Ph.D.) sent the following comments: ------------------------------------------------------------ We are looking for the following references, which are not available locally in Taiwan. Anyone can send us a copy will be highly appreciated. 1) PAH Gene Mutation Analysis Consortium Newsletter (October, 1994). 2) PAH Gene Mutation Analysis Consortium Newsletter (December, 1993). Thank you in advance! --------------------------------------------------------------------- Kwang-Jen Hsiao, Ph.D. Professor, Institute of Genetics Investigator National Yang-Ming University Clin. Biochem. Res. Laboratory Peitou P.O. Box 2-207 Dept. of Medical Res. & Education Taipei, Taiwan 11216 Veterans General Hospital-Taipei Tel: 886-2-875-7401 E-mail: hsiao@mail.pmf.org.tw Fax: 886-2-873-3517 hsiao@ms1.hinet.net --------------------------------------------------------------------- ------------------------------------------------------------ Server protocol: HTTP/1.0 Remote host: Remote IP address: 192.72.15.20 *************************************************************************** >From R.Clarke@UNSW.EDU.AUTue Apr 9 13:41:46 1996 Date: Mon, 18 Mar 1996 23:30:41 +0100 From: Raymond Clarke <R.Clarke@UNSW.EDU.AU> R.Clarke@unsw.edu.au (Raymond Clarke) sent the following comments: ------------------------------------------------------------ We want to characterise squamous cell carcinomas. We need advice on markers that may help us get a handle on a set of very aggressive tumours that we have been studying. We would appreciate an experienced collaborator for this study. ------------------------------------------------------------ Server protocol: HTTP/1.0 Remote host: Remote IP address: 129.94.50.56 ********************************************************************** >From BrownEB_at_USNORALL@CCIP.PERKIN-ELMER.COMTue Apr 9 13:42:53 1996 Date: Wed, 20 Mar 1996 10:16:57 -0500 (EST) This message was originally submitted by BrownEB_at_USNORALL@CCIP.PERKIN-ELMER. COM to the HUM-MOLGEN list at NIC.SURFNET.NL. Where could I find out how many times a particular paper has been referenced? Please let me know. e-mail address: BrownEB@perkin-elmer.com ***************************************************************************** >From pmorris@MEDICINE.ADELAIDE.EDU.AUTue Date: Thu, 21 Mar 1996 17:05:50 +0900 From: Phillip Morris <pmorris@MEDICINE.ADELAIDE.EDU.AU> This message was originally submitted by pmorris@MEDICINE.ADELAIDE.EDU.AU to the HUM-MOLGEN list at NIC.SURFNET.NL. I am interested in viewpoints on the usage and meaning of the terms "polymorphism" and "mutation". There are numerous definitions in many texts but it may be reasonable to summarize them in their most basic form as: polymorphism - the coexistence of two or more variants in a population mutation - a variant in the population that differs from "wild type" The definitions of polymorphism that I have come across often, but not always, involve some minimum value of the frequency of the least abundant allele. However, this allele frequency value varies from definition to definition, between >0.1 and >1x10-9 (the approximate mutation frequency of any given base in the genome). Mutation definitions also imply that the allele frequency of mutations must be less than 50% since it is not wild type? I find it difficult to distinguish between the two terms and I would appreciate hearing ANY thoughts on the matter. I am particularly interested in WELL referenced definitions or anecdotes about the derivation or evolution of these terms. I would also like comments on the idea that, in general human genetics usage, polymorphisms are considered to be harmless while mutations are presumed to be deleterious. All comments are welcomed. Phillip Morris __________________________________________ C. Phillip Morris Department of Chemical Pathology Women's and Children's Hospital North Adelaide, SA 5006 Australia Tel. 61 8 204-7330 Fax. 61 8 204-7100 E-mail pmorris@medicine.adelaide.edu.au _________________________________________ *************************************************************************** >From 108LAS@COSMOS.WITS.AC.ZATue Apr 9 13:45:33 1996 Date: Mon, 25 Mar 1996 10:59:27 +0100 From: Lara Stein <108LAS@COSMOS.WITS.AC.ZA> Reply to: Human Molecular Genetics Editors <ED-MOLGEN@nic.SURFnet.nl> To: Multiple recipients of list ED-MOLGEN <ED-MOLGEN@nic.SURFnet.nl> Subject: "mad-cow disease" Resent-Date: Mon, 25 Mar 1996 10:59:27 +0100 Resent-From: owner-ed-molgen@HEARN.NIC.SURFNET.NL Resent-To: A.A.Bergen@AMC.UVA.NL I am interested to know the origin of the scare in Britain about "mad cow disease"/scrapie. Has an article been published in the scientific literature suggesting that humans can be affected by eating beef from infected cattle? Lara Stein University of Witwatersrand South Africa 108las@cosmos.wits.ac.za ******************************************************************** >From mimipeg@UCLINK2.BERKELEY.EDUTue Apr 9 13:51:44 1996 Date: Mon, 25 Mar 1996 18:00:40 -0800 From: Margaret Conrad <mimipeg@UCLINK2.BERKELEY.EDU> This message was originally submitted by mimipeg@UCLINK2.BERKELEY.EDU to the HUM-MOLGEN list at NIC.SURFNET.NL. From: Peggy Conrad/ Genetic Counseling Student/ UC Berkeley Subject: Acetylation polymorphism/ debrisoquine polymorphism I would appreciate hearing from anyone who may be aware of a recent comprehensive review article on the above subject. I am particularly interested in the clinical implications for the different phenotypes, with regard to drug response and spontaneous other disorders. Please respond via my email. Thank You. *************************************************************************** >From l.nasir@UDCF.GLA.AC.UKTue Apr 9 13:47:33 1996 Date: Wed, 27 Mar 1996 12:22:43 +0000 (GMT) From: lubna nasir <l.nasir@UDCF.GLA.AC.UK> Reply to: Human Molecular Genetics Editors <ED-MOLGEN@nic.SURFnet.nl> To: Multiple recipients of list ED-MOLGEN <ED-MOLGEN@nic.SURFnet.nl> Subject: CALL Resent-Date: Wed, 27 Mar 1996 12:22:43 +0000 (GMT) Resent-From: owner-ed-molgen@HEARN.NIC.SURFNET.NL Resent-To: A.A.Bergen@AMC.UVA.NL This message was originally submitted by l.nasir@UDCF.GLA.AC.UK 1) We are looking for researchers who may have a p53 riboprobe that we may use against a couple of Northern Blotts. 2) We are also interested in contacting anyone who may have a feline cDNA library. Thanks Lubna Nasir Dr. Lubna Nasir/S. Duthie Dept Veterinary Clinical Studies University of Glasgow Veterinary School Bearsden Road Glasgow G61 1QH Scotland UK Tel: +44-0141-330-6918/5730 Fax: +44-0141-330-6996 Dr. Lubna Nasir Dept Veterinary Clinical Studies University of Glasgow Veterinary School Bearsden Road Glasgow G61 1QH Scotland UK Tel: +44-0141-330-6918/5730 Fax: +44-0141-330-6996 ************************************************************************* >From hamilton@EXPRESS.CATue Apr 9 13:47:54 1996 Date: Sun, 31 Mar 1996 21:34:42 +0200 hamilton@express.ca (HAMILTON) sent the following comments: ------------------------------------------------------------ LOOKING FOR ELIZABETH LIEW'S E MAIL ADRESS. SHE STUDIES GENETICS AT UBC.I WOULD LIKE TO CONTACT HER. :) IAN HAMILTON ------------------------------------------------------------ Server protocol: HTTP/1.0 Remote host: ppp3.express.ca Remote IP address: 206.12.15.34