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To: Multiple recipients of list HUM-MOLGEN <HUM-MOLGEN@NIC.SURFNET.NL>
Subject: LITE: preview Molecular Medicine November 1995
From: Arthur Bergen <bergen@AMC.UVA.NL>
Date: Tue, 31 Oct 1995 13:57:45 +0100

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Molecular Medicine
TABLE OF CONTENTS
November 1995

Series: Molecular Medicine Institutions
Cold Spring Harbor Laboratory
B. Stillman

Opinion
Glutamine Repeats as Polar Zippers: Their Role in Inherited
Neurodegenerative Disease
M.F. Perutz

Minireview
Antigen-Specific Therapy for Autoimmune Disease: Prospects for the
Prevention of Insulin-Dependent Diabetes
L.C. Harrison

In This Issue
Summaries of Articles

Original Articles
Interferon-g Induced Oligodendrocyte Cell Death: Implications for the
Pathogenesis of Multiple Sclerosis
T. Vartanian, Y. Li, M. Zhao, and K. Stefansson
Submitted by R. Cotran

Low Copy Number and Limited Variability of Proviral DNA in Alveolar
Macrophages from HIV-1 Infected Patients: Evidence for Genetic Differences
in HIV-1 Between Lung and Blood Macrophage Populations
K. Nakata, M. Weiden, T. Harkin, D. Ho, and W.N. Rom
Submitted by L. Philipson

Compounds that Target Novel Cellular Components Involved in HIV-1
Transcription
S.T. Butera, B.D. Roberts, J.W. Critchfield, G. Fang, T. McQuade,
S.J. Gracheck, and T.M. Folks
Submitted by A.S. Fauci

VH3-21 B Cells Escape from a State of Tolerance in Rheumatoid Arthritis
and Secrete Rheumatoid Factor
X. He, J.J. Goronzy, W. Zhong, C. Xie, and C.M. Weyand
Submitted by G.J.V. Nossal

Localization of Macrophage Migration Inhibitory Factor (MIF) to Secretory
Granules within the Corticotrophic and Thyrotrophic Cells
of the Pituitary Gland
T. Nishino, J. Bernhagen, H. Shiiki, T. Calandra, K. Dohi, and R. Bucala
Submitted by A. Cerami

Detection of Circulating Tumor Cells in Colorectal Cancer by Immunobead-PCR
is a Sensitive Prognostic Marker for Relapse of Disease
J.E. Hardingham, D. Kotasek, R.E. Sage, M.C. Eaton, V.H. Pascoe,
and A. Dobrovic
Submitted by G.J.V. Nossal

Administration of Neutralizing Antibodies to Interleukin-6 (IL-6) Reduces
Experimental Autoimmune Encephalomyelitis and is Associated with Elevated
Levels of IL-6 Bioactivity in Central Nervous System and Circulation
K. Gijbels, S. Brocke, J.S. Abrams, and L. Steinman
Submitted by I. Weissman

Differences in the Expression of Heat-Shock Proteins and Antioxidant Enzymes
Between Human and Rodents Pancreatic Islets: Implications for the Pathogenesis
of Insulin-Dependent Diabetes Mellitus
N. Welsh, B. Margulis, L.A.H. Borg, H.J. Wiklund, J. Saldeen, M. Flodstr=F6m
M.A. Mello, A. Andersson, D.G. Pipeleers, C. Hellerstr=F6m, and D.L. Eizirik
Submitted by D.F. Steiner

Local Expansion of Allergen-Specific CD30+Th2-Type gd T Cells in Bronchial
F.Spinozzi, E. Agea, O. Bistoni, N. Forenza, A. Monaco, B. Falini,
G. Bassotti, F. DeBenedictis, F. Grignani, and A. Bertotto
Submitted by S.F. Schlossman

Parallel Induction of Heme Oxygenase-1 and Chemoprotective Phase 2 Enzymes
by Electrophiles and Antioxidants: Regulation by Upstream Antioxidant
Responsive Elements (ARE)
T. Prestera, P. Talalay, J. Alam, Y.I. Ahn, P.J. Lee, and A.M.K. Choi

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