David J. Triggle (Editor), Murali Gopalakrishnan (Editor), David Rampe (Editor), Wei Zheng (Editor), Raimund Mannhold (Series Editor), Hugo Kubinyi (Series Editor), Gerd Folkers (Series Editor)
Hardcover - 492 pages
April 2006 - Wiley-VCH, Weinheim
Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology.
After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development.
For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.
=> Sample Chapter
Table of Contents
Structure and Function of Ion Channels
Drug Interaction at Ion Channels
Channel Subtype Selectivity
Genetic and Acquired Channelopathies
Long QT Syndrome
Safety Issues in Ion Channel Drug Development
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