The Development of Human Gene Therapy (Cold Spring Harbor Monograph Series, 36)
by Theodore Friedmann (Editor)
Cold Spring Harbor Laboratory
Contributors from inside the discipline trace the unconventional 30- year development of gene therapy, which was widely accepted by the medical community and society at large long before there were any practical clinical results. They describe specific topics such as retroviral and lentiviral vectors, advances in synthetic gene-delivery system technology, naked DNA gene transfer in mammalian cells, the hematopoietic system as a target for gene therapy, suicide genes, the logic of anti-angiogenic gene therapy, apoptosis as a goal of cancer gene therapy, therapy for HIV and other viral infections, public policy and regulatory issues, and ethical issues in human gene transfer research.Book News, Inc.®, Portland, OR
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