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virtual library in human genetics and molecular biology

Series: Molecular Medicine Institutions
The Howard Hughes Medical Institute
P.W. Choppin

Commentary
Beyond Drug Regulation: The Science of Drug Evaluation
A. Fleming

Review
Looking Beneath the Surface: The Cell Death Pathway of Fas/APO-1 (CD95)
B.Z. Stanger
Submitted by P. Leder

Meeting Report
Cancer: The Interface Between Basic and Applied Research

In This Issue
Summaries of articles

Original Articles
Expression of Inflammatory Cytokines and Inducible Nitric Oxide Synthase in Brains of SIV-Infected Rhesus Monkeys: Applications to HIV-Induced Central Nervous System Disease
T.E. Lane, M.J. Buchmeier, D.D. Watry, and H.S. Fox
Submitted by F.E. Bloom

Role of IgE Immune Complexes in the Regulation of HIV-1 Replication and Increased Cell Death of Infected U1 Monocytes: Involvement of CD23/FceRII Mediated Nitric Oxide and Cyclic AMP Pathways
F. Ouaaz, F.W. Ruscetti, B. Dugas, J. Mikovits, H. Agut, P. Debré, and M.D. Mossalayi
Submitted by S. Moncada

Reduction of Food Intake and Weight Gain by the ob Protein Requires a Specific Secondary Structure and is Reversible
K. Giese, W.J. Fantl, C. Vitt, J.C. Stephans, L. Cousens, M. Wachowicz, and L.T. Williams
Submitted by F.E. Cohen

Prenatal Diagnosis for Recessive Dystrophic Epidermolysis Bullosa in Ten Families by Mutation and Haplotype Analysis in the Type VII Collagen Gene (COL7A1)
A.M. Christiano, S. LaForgia, A.S. Paller, J. McGuire, H. Shimizu, and J. Uitto
Submitted by D.J. Prockop

Mutation Detection in Machado-Joseph Disease Using Repeat Expansion Detection
K. Lindblad, A. Lunkes, P. Maciel, G. Stevanin, C. Zander, T. Klockgether, T. Ratzlaff, A. Brice, G.A. Rouleau, T. Hudson, G. Auburger, and M. Schalling
Submitted by H. Wigzell

Molecular Cloning, Chromosomal Mapping and Characterization of the Human Cardiac Specific Homeobox Gene hCsx
D. Turbay, S.B. Wechsler, K. McQuate Blanchard, and S. Izumo
Submitted by T. Yamada

Analysis of the Structure and Expression of the Augmenter of Liver Regeneration (ALR) Gene
R. Giorda, M. Hagiya, T. Seki, M. Shimonishi, H. Sakai, J. Michaelson, A. Francavilla, T.E. Starzl, and M. Trucco
Submitted by G.J.V. Nossal

The 55kDa Tumor Necrosis Factor Receptor and CD95 Independently Signal Murine Hepatocyte Apoptosis and Subsequent Liver Failure
M. Leist, F. Gantner, G. Künstle, I. Bohlinger, G. Tiegs, H. Bluethmann, and A. Wendel
Submitted by E. Beutler

Retroviral Vector Design for Gene Therapy of Cancer: Specific Inhibition and Tagging of BCR-ABLp190 Cells
B. García-Hernández and I. Sánchez-García
Submitted by I. Pastan

Response of Mycobacterium tuberculosis to Reactive Oxygen and Nitrogen Intermediates
T.R. Garbe, N.S. Hibler, V. Deretic
Submitted by S. Falkow

The Immunoregulatory Mediator Macrophage Migration Inhibitory Factor (MIF) Catalyzes a Tautomerization Reaction
E. Rosengren, R. Bucala, P. Ã…man, L. Jacobsson, G. Odh, C.N. Metz, and H. Rorsman
Submitted by S. Moncada

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Molecular Medicine Calendar

MOLECULAR MEDICINE is the official journal of the Molecular Medicine Society (MMS), an exciting new organization devoted to the
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