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Editorial
Molecular Medicine: the Future of Biomedical Science and Clinical Practice
A. Cerami and K.S. Warren

Opinion
Gene Therapy: Hopes, Hypes and Hurdles =
I.M. Verma

In This Issue
Summaries of Articles

Original Articles

Role of Macrophage Oxidative Burst in the Action of Anthrax Lethat Toxin
P. Hanna, B. Kruskal, R.A. Ezekowitz, B. Bloom, and R.J. Collier*

High Prion and PrPSc Levels but Delayed Onset of Disease in Scrapie-Inoculated Mice Heterozygous for a Disrupted PrP Gene
H. B eler, A. Raber, A. Sailer, M. Fischer, A. Aguzzi, and C. Weissmann

Pentoxifylline and Other Protein Kinase C Inhibitors Down-Regulate HIV-LTR NF-kB Induced Gene Expression
D.K. Biswas, C.M. Ahlers, B.J. Dezube, and A.B. Pardee

The Evolutionarily Conserved Ribosomal Protein L23 and the Cationic Urease b-Subunit of Yersinia enterocolitica O:3 Belong to the Immunodominant Antigens of Yersinia-Triggered Reactive Arthritis
A.K.H. Mertz, A. Daser, M. Skurnik, K. Wiesm ller, S. Batsford, J. Braun P. Wu, H. Appel, A. Distler, and J. Sieper Submitted by N.A. Mitchison

Clonal Hematopoiesis and Acquired Thalassemia in Common Variable Immunodeficiency
M. Belickova, H.W. Schroeder, Jr., Y.L. Guan, J. Brierre, S. Berney, M.D. Cooper, and J.T. Prchal

X Chromosome Inactivation Patterns Correlate with Fetal-Placental Anatomy in Monozygotic Twin Pairs: Implications for Immune Relatedness Concordance for Autoimmunity
V. Trejo, C. Derom, A.Vlietinck, W. Ollier, A. Silman, G. Ebers, R. Derom, and P.K. Gregersen
Submitted by K.S. Warren

Circulating Fibrocytes Define a New Leukocyte Subpopulation That Mediates Tissue Repair
R. Bucala, L. Spiegel, J. Chesney, M. Hogan, and A. Cerami

Glucocerebrosidase Mutations in Gaucher Disease
E. Beutler, A. Demina, and T. Gelbart

Lipopolysaccharide Signals Activation of Tumor Necrosis Factor Biosynthesis through the Ras/Raf-1/MEK/MAPK Pathaway
T.D. Geppert, C.E. Whitehurst, P. Thompson, and B. Beutler
Submitted by A. Cerami

The Molecular Basis of Increased Glomerulosclerosis after Blockade of the renin Angiotensin System in Growth Hormone Transgenic Mice
E.P. Peten, L.J. Striker, A. Fogo, I. Ichikawa, A. Patel, and G.E. Striker
Submitted by D.K. Peters

Molecular Medicine Database


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MOLECULAR MEDICINE is the official journal of the Molecular Medicine Society (MMS), an exciting new organization devoted to the re-integration of medical research at the molecular level.

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