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Port Coquitlam
C. - B.
Canada
Toll free: +011-236-983-6419 (SMS)
Phone: 6049458408
Fax: +011-604-941-9022
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Description:
The Process of Drug Synthesis for the Agonist to Vit D3 at PharmaCare(R). I. Scope of Pharma Care with VitD3-Agonist: 1. A potentially lucrative drug to address milk fever in Vet Care with preparturient cows ready for milking after calving. 2. Treatment of Osteoporosis together with Ca2+ and Strontium to strengthen bone density in this condition. 3. Treatment of the Systemic Chronic Inflammatory (SCI) condition including major ones: atherosclerosis, diabetes type 2, certain Cancers, multiple sclerosis, rheumatoid arthritis, kidney disease and Alzheimers. 4. Skye Blue also has a commitment to adapt a platform like BioHarvest(TM)'s to production using early Spring grass and legume cells for complex carbohydrates (CHOs) as nutraceutical supplements banking on theories of their effects on lower gut digestion and its microbiome, gut development and animal well-being and the gut's connectedness with immunological, endocrinological, cardiological and neurological systems. II. Bio-Organic Synthesis: Organic Chemical and Mutational Microbial Steps *, **, *** (7 synthetic steps + 22 bioenzymes with a botanical platform = 29 step count)*: 1. photochemical, hv Lanosterol -----> 7 steps -----> Lanosteral -----> 18 steps -----> 7-dehydrocholesteral ----------------------------> The Flores Synthesis (Pro-vitamin D3 2. thermal or heat Agonist) liver enzyme skin cells or kidney enzyme Cholecalciferal (Vit D3) -------------> Calcifedial or Calcidial** ----------------> Calcitrial step step (active Vit D3 - the Agonist) * Total Steps to Calcitrial = 29. ** This cpd. is stable, to be taken orally (tab or cap). *** Comments: 1. Pro-VitD3 (which Skye Blue is committing to at this time rather than Pro-VitD2) has to undergo spontaneous isomerization with UV irradiation and thermal treatment. 2. It is a research priority to ascertain the total yield of the Flores Synthesis (steps #1-#7) for precursor Lanosteral which is fed via electrochemical perfluence to plant cells in a platform (GMO) similar to BioHarvest(TM)'s for botanical biosynthesis of pharma, nutraceuticals, foods, flavourings and dyes. 3. Skye Blue plans to partner with BioHarvest(TM), synthetic pioneers with botanical systems, in future, hopefully in tab or injection form, for e. g. as calcifedial or calcidial. 4. Pros vs cons using Vit D3 vs Vit D2 will be outlined later in terms of: 1) absorption and 2) effectiveness. III. The Scope of PharmaCare(R) with VitD3-Agonist: 1. A potentially lucrative drug to address milk fever in Vet Care with preparturient cows ready for milking after calving. 2. Treatment of Osteoporosis together with Ca2+ and Strontium to strengthen bone density in this condition. 3. Treatment of the Systemic Chronic Inflammatory (SCI) condition including major ones: atherosclerosis, diabetes type 2, certain Cancers, multiple sclerosis, rheumatoid arthritis, kidney disease and Alzheimers. 4. Skye Blue also has a commitment to adapt a platform like BioHarvest(TM)'s to production using early Spring grass and legume cells for complex carbohydrates (CHOs) as nutraceutical supplements banking on theories of their effects on lower gut digestion and its microbiome, gut development and animal well-being and the gut's connectedness with immunological, endocrinological, cardiological and neurological systems. (c) D. A. Flores. 2026-2059. Skye Blue Press Corporation. Port Coquitlam BC Canada V3B 1G3.
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Last update of this entry: October 25, 2026
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