Epigenomics.  This includes targetting RNA-based biologics with highly engineered active TF elements through TFE that are epigenetic interacting with commensal endogastric, in-residence probiotic n-plasmids (native plasmids) of specialized production animals, to accelerate digestive related processes amongst the strategically significant subpopulations of fibrolytic fungi, ligninophiles and those needing energy boosting from available soluble sugar digests for boosted protein synthesis ("storage", note: vs. "surrogate" or GMO coded proteins) via i) boosting synthesis and ii) boosting limiting "essential" amino acids in bacterial protein metabolism (bacterial spp. needing further investigation- viz. robustness, precision, accuracy- all factors to determine for the regulation (non-coding sequences of DNA) impacting the specific coding sequences of DNA and their "structural gene cassettes" of great interest here.

 

Author Bio.  The author in 1988 proposed in his exclusive Literature Survey and accompanying peer-reviewed mini-survey or review with the leading J. Biotechnol. at the Uni. in NSW, Australia (Sydney) during graduate studies surveying possible strategies by using byproduct class of feeds used by the livestock husbandry industry, their endogastric manipulation, mainly plasmid-based, together with byproducts of good quality (conventional feeds are considered of v. good to excellent depending on further modification and processing) what are referred to in the feed industry as: i) energy concentrates [supplements to basal ration to boost nutritive value (N. V.)] and ii) protein concentrates [supplements to basal ration to boost protein supply and ration nutritive value (N.V.)]. The author would like to comment to the reader that technology has advanced recently, remarkably, using the previously described non-GMO technology using RNA-based gene silencing also predicted to make headway in Cancer research and other areas in Medicine not just Agri-Food, Energy and Biorecyclables or materials.

 

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Our original reference, one only of its kind is found here (CLICK): https://www.sciencedirect.com/science/article/abs/pii/0168165689900321#:~:text=Journal%20of%20Biotechnology%2C%2010%20%281989%29%2095%20-%20112,microbial%20biomass%20component%20from%20feeding%20low%20quality-based%20diets.