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Magnusstr.11
D-12489 Berlin
Germany
Phone: ++49 30 20616265 Fax: ++49 30 20616267 Please notice: This entry hasn't been updated by the submitting company for more than 2 years. It could be possible that this company doesn't longer exists.
Description:
Company objectives Proteome Factory AG offers contract research and fee-for-service analyses in the field of protein analysis, analysis and characterization of biosimilars and therapeutic/recombinant proteins, proteome analysis (proteomics), protein identification characterization, protein sequencing (N-terminal, internal sequencing and sequencing of complete proteins). Proteome Factory AG offers and develops new technologies for high throughput differential proteome analysis. Contract research service / fee-for-service: - Proteomics (gel-based and gel-free approaches): - Protein analysis and characterization of therapeutic and recombinant proteins and peptides
- Biomarker discovery and identification
- Biomarker profile discovery and identification
- Protein and peptide target discovery and identification
- Identification of regulated proteins and protein species
- Optimization of fermentation processes
- Optimization of plant breeding
- Pharmaco proteomics
- Identification of vaccine candidates
- Immuo proteomics
- Phospho proteomics
- Membrane proteomics
Technology plattform: - high resolution mass spectrometry / nanoLC-MS - high resolution 2D electrophoresis 23x30cm, 40x30 cm (separation of up to 10000 protein spots) - 2DLC-ESI-MSMS (label free, ITRAQ, MeCAT) - depletion of high abundant plasma/CSF proteins by affinity depletion - prefractionation (e.g. phospho proteins, membrane proteins) - Blue native PAGE / SDS-PAGE etc. - Identification, sequencing and characterization of proteins, biosimilars and biobetters - protein ID by nanoLC-ESI-MSMS of individual or low complex protein samples
- protein ID by MALDI-TOFTOF-MS of individual proteins
- MudPIT (multi dimensional protein identification technique) of complex protein samples
- analysis of phosphorylation sites
- analysis of glycosilation sites
- analysis of PTMs (post-translational modification)
- analysis of deamidation and oxidation, lysine clipping etc.
- AA sequening by mass spectrometry
- Protein sequencing - N-terminal protein sequencing
- N-terminal peptide sequencing
- Internal protein sequencing
- Sequencing of complete proteins by combination of mass spectrometry, N-terminal sequencing and HPLC fractionation of proteolytic peptides generated by protein cleavage with several proteases/chemicals
- Analysis and Quality Control of protein and peptide samples etc. - Analysis, identification and characterization of products and batches
- Analysis of the composition of complex protein mixtures (protein display)
- Comparison of the composition of complex protein mixtures (e.g. product comparison)
- Analysis of protein and peptide stability
- Analysis of the pharmacokinetic of protein and peptides, e.g. antibodies
- Assistance for optimisation of fermentation and production by protein analysis
Products: - Kits:
- MeCAT (metal coded tagging) multiplex kit for proteomics and absolute quantification of proteins and peptides by ICP-MS
- Breakable DPAGE kit for 2DE and SDS-PAGE (DPAGE allows the dissolving of PAGE after protein separation)
- FireSilver kit - high sensitive silver staining kit, highly compatible with protein ID by MS
- FireRuth protein fluorescent staining solution, ready-to-use
- FirePhospho-protein enrichment kit (coming soon)
- Proteomics Automatisation:
- spotXpress- HTS spotpicking robot (up to 800 spot/hour)
- spotDigest 96 - sample preparation robot for protein identification of protein spots cut by spotXpress
Selected Categories:
Last update of this entry: September 28, 2021
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