home genetic news bioinformatics biotechnology literature journals ethics positions events sitemap


UBBFriend: Email This Page to Someone!
  HUM-MOLGEN
  Open Topic Forum
  Auditory distractibility - beyond only genetics

Post New Topic  Post A Reply
profile | register | preferences | faq | search

next newest topic | next oldest topic
Author Topic:   Auditory distractibility - beyond only genetics
pgd
Member
posted 12-09-2002 08:17 PM     Click Here to See the Profile for pgd     Edit/Delete Message Reply w/Quote
Regarding the general idea of sound sensitivities and sound epilepsy as having a genetic basis, sound sensitivities go beyond a type of epilepsy to other neurological challenges including ADHD, CAPD - Central Auditory Processing Disorder, hyperacusis and so on.
http://www.nimh.nih.gov/publicat/adhd.cfm
http://home.earthlink.net/~mcoleman/cpdadd.html
http://www.hyperacusis.net/
http://www.epilepsyfoundation.org/

---

Author Topic: Gene For Epilepsy Affects Brain Areas Responsible For Sound Perception
DSOUZA
Moderator posted 02-03-2002 04:56 AM
---
By studying families whose members have an uncommon form of epilepsy, researchers have revealed a new gene, and possibly a new mechanism, for the condition.
Ruth Ottman and colleagues at Columbia University in New York City have identified mutations in a gene called LGl1 in individuals who have a type of epilepsy that manifests as "sound" hallucinations -- in other words, during a seizure affected individuals will often "hear" sounds that are not real (Nature Genetics). These symptoms suggest that the epilepsy arises from the abnormal functioning of a specific area of the brain responsible for sound perception. Although inheriting a mutated copy of the gene does not guarantee getting epilepsy, the disorder will develop in about 70 percent of cases.
A handful of genes that predispose to other types of epilepsy in humans are known -- all of which code for proteins that let chemical signals in and out of brain cells. While the precise function of the LGl1 gene is unknown, it does not appear to fall in the same category but may be necessary for proper brain development.
Previous studies have indicated that loss of the LGI1 gene promotes the progression of certain types of brain tumors. However, Ottman's group found no evidence for an increased risk for developing brain cancer in people carrying a mutant copy of the gene.

Author contact:

Ruth Ottman
Columbia University,
New York, NY,
USA
Tel: +1 212 305 9188
Email: ro6@columbia.edu

Published online

(C) Nature Genetics press release.


[This message has been edited by DSOUZA (edited 02-03-2002).]


IP: 66.81.140.126

All times are ET (US)

next newest topic | next oldest topic

Administrative Options: Close Topic | Archive/Move | Delete Topic
Post New Topic  Post A Reply
Hop to:

Contact Us | HUM-MOLGEN

Copyright by HUM-MOLGEN 1995-2015

Powered by: Ultimate Bulletin Board, Version 5.44a
© Infopop Corporation (formerly Madrona Park, Inc.), 1998 - 2000.