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 SNP-L Renovated
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| Author | Topic: SNP-L Renovated |
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Bert Gold Member |
posted 05-08-2007 06:32 PM
   
SNP-L is an electronic mailing list for members of the biomedical research community interested in studying the relationship between single nucleotide polymorphisms and human disease. SNP-L grew out of my frustration with the fact that, although the human genome sequence is now available, there are not enough tools for large epidemiologic studies of SNPs. Projects such as the HapMap coupled with work at the Broad Institute and through the sequencing centers identified large numbers of SNPs and housed these at dbSNP, however; these still need to be verified and validated and their frequency in various populations determined. In addition, only by studying the frequency of SNPs in disease at-risk populations, will we come to know their significance. The informatic tools for discovering these correlations are emerging, and access to databases containing genotypes and affection status are slowly but surely being made available to qualified researchers. Whole genome association studies have now been published on Prostate cancer, obesity, Type II Diabetes, and Heart Disease. More will be forthcoming in the literature shortly. We will be discussing the opportunities and challenges of groundbreaking research here. So, there will be a great deal to discuss on this list. You can sign up for the list on the SNP-L webpage which is: or by writing to me at: goldb@ncifcrf.gov Bert Gold, Ph.D., FACMG IP: 129.43.13.116 |
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