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  Open Enrollment for Relapsed DLBCL - A Phase IIb Vorinostat Study

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Author Topic:   Open Enrollment for Relapsed DLBCL - A Phase IIb Vorinostat Study
posted 07-17-2005 09:26 PM     Click Here to See the Profile for Administrator     Edit/Delete Message Reply w/Quote
Dear Colleague:

Merck & Co., Inc. is sponsoring a clinical trial for patients with relapsed Diffuse Large B Cell Lymphoma (DLBCL) throughout the United States and in selected ex-US countries.

This study is open to patients diagnosed with advanced Diffuse Large B Cell Lymphoma who have progressive, persistent, or recurrent disease following standard first line therapy with CHOP (or equivalent anthracycline-containing regimen) and at least one systemic salvage regimen (including but not limited to autologous hematopoietic stem cell transplant). All patients in this non-randomized, open-label, Phase IIb study will receive the oral histone deacetylase inhibitor vorinostat (Suberoylanilide Hydroxamic Acid, SAHA).

In the United States, participating study sites are located in the following states:

New Jersey
New York
North Carolina
Washington, DC

More information about this study can be found at: http://clinicaltrials.gov (Study ID: 2004_029 NCT00097929), or http://www.cancer.gov/Search/SearchClinicalTrialsAdvanced.aspx (Protocol ID: 2004_029 )

To refer patients for evaluation for inclusion in this protocol,
please call 1-888-577-8839 (toll free).

Please feel free to forward this message to other health care providers who might be interested in learning more about the study and/or referring patients into this study.


Sophia Randolph, M.D., Ph.D.
Associate Director
Clinical Molecular Profiling
Merck & Co., Inc.


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