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HUM-MOLGEN
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![]() AnaSpec Launches Industry’s First Amino Acid Pre-loaded Hydrazide Resins
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| Author | Topic: AnaSpec Launches Industry’s First Amino Acid Pre-loaded Hydrazide Resins |
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anaspec Member |
Native Chemical Ligation (NCL) has been one of the most used bioconjugation methodologies for synthesis of macromolecules. NCL requires a peptide thioester and another peptide moiety containing a free cysteine at the N-terminus. However, peptide thioester synthesis is technically challenging due to its instability. The use of a peptide hydrazide is more recommended.
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