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  GPCR and PDE Cell Lines and Assays for Drug Screening

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Author Topic:   GPCR and PDE Cell Lines and Assays for Drug Screening
posted 02-28-2013 09:25 PM     Click Here to See the Profile for amalykh   Click Here to Email amalykh     Edit/Delete Message Reply w/Quote
Capital Biosciences offers GPCR cell lines for reserach and drug development applications.

Cells expressing G-protein coupled receptors (GPCR) or cyclic nucleotide phosphodiesterases (PDEs) are usefull tools for drug screening. Having reliable assays for GPCR or PDE activity makes these cell lines even more attractive.

Advantages of ACTOne Technology as the key platform used for the development of Cell Based Assay for GPCR and PDE:

Use of a modified cyclic nucleotide-gated (CNG) ion channel as a biosensor
Ultrasensitive response to cAMP fluctuations
Suitable for high-throughput screening of GPCR-target molecules in living cells
Companion assay kits available for easy use
Cost effective system for drug discovery and other related studies

Please contact us at info@capitalbiosciences.com
or call at 1-(800)475-2812

[This message has been edited by amalykh (edited 02-28-2013).]


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