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Author Topic:   GPCR focused libraries - new products from OTAVA
grischenko
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posted 10-02-2009 12:12 PM     Click Here to See the Profile for grischenko   Click Here to Email grischenko     Edit/Delete Message Reply w/Quote
We are happy to offer Otava’s two GPCR-related focused libraries:

1. GPCR Antagonist focused library (4953 compounds)
2. GPCR Agonists focused library (466 compounds)

The libraries have been designed with QSAR using training set of compounds active towards various GPCRs . The libraries contain drug-like compounds having the following predicted activities:

GPCR Antagonist focused library
5 Hydroxytryptamine antagonist
Acetylcholine muscarinic antagonist
Adenosine receptor antagonist
Alpha adrenoreceptor antagonist
Beta adrenoreceptor antagonist
Endothelin receptor antagonist
GABA receptor antagonist
Dopamine antagonist
Glucagon receptor antagonist
Glutamate receptor antagonist
Histamine antagonist
Melatonin antagonist
Neuropeptide antagonist
Prostaglandin antagonist
Thromboxane antagonist
Vasopressin 1 antagonist

GPCR Agonist focused library
5 Hydroxytryptamine agonist
Acetylcholine muscarinic agonist
Alpha adrenoreceptor agonist
Beta adrenoreceptor agonist
Cholecystokinin agonist
Dopamine agonist
Dopamine autoreceptor agonist
GABA receptor agonist
Melatonin agonist


All compounds are in stock, cherry-picking is available. These libraries are proposed for screening in GPCR-associated research and drug development.

OTAVA Ltd.
150 Zabolotnogo St.
Kyiv, 03143, Ukraine
Tel./Fax: +380 44 522 2458
info@otavachemicals.com www.otavachemicals.com

OTAVA – North American Division
55 Ellerslie Ave., Suite 524
Toronto, Ontario, M2N 1X9
Canada
Tel.: 1-416-305-9979
Fax: 1-866-881-9921
(Toll-free in US & Canada)
north.america@otavachemicals.com

IP: 217.27.154.230

All times are ET (US)

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