home genetic news bioinformatics biotechnology literature journals ethics positions events sitemap


UBBFriend: Email This Page to Someone!
  HUM-MOLGEN
  Biotechnical requests and sources
  AnaSpec Offers Fluo-3 - A High Affinity Fluorescent Calcium Indicator

Post New Topic  Post A Reply
profile | register | preferences | faq | search

next newest topic | next oldest topic
Author Topic:   AnaSpec Offers Fluo-3 - A High Affinity Fluorescent Calcium Indicator
anaspec
Member
posted 03-27-2008 10:22 PM     Click Here to See the Profile for anaspec   Click Here to Email anaspec     Edit/Delete Message Reply w/Quote
San Jose, CA March 27, 2008

Calcium plays a vital role in the specific and selective regulation of major cellular processes and is central in the regulation of cardiac contractility, growth and gene expression. Calcium indicators are small molecules that can respond to the binding of Ca2+ ions by changing their spectral properties. Recognizing the need for versatile tools for the detection of calcium, AnaSpec offers Fluo-3, a high affinity fluorescent calcium indicator.

Fluo-3 absorbs at approximately 506 nm and emits at 526 nm when bound to calcium. In the absence of calcium it is practically non-fluorescent. The higher Kd and longer excitation wavelength of Fluo-3 can have significant advantages over other indicators because of the reduced interference with sample autofluorescence. It demonstrates efficient excitation with laser-based instrumentation, including confocal laser scanning microscopes. It has been widely used for flow cytometry and is one of the imaging methods of intracellular calcium flux that is associated with GPCR dynamics.
Company Info
AnaSpec, Inc. is a leading provider of integrated proteomics solutions to pharmaceutical, biotech, and academic research institutions throughout the world. With a vision for innovation through synergy, AnaSpec focuses on three core technologies: peptides, detection reagents (dyes, assay kits, & antibodies), and combinatorial chemistry.

For more information, visit www.anaspec.com


IP: 68.120.108.218

All times are ET (US)

next newest topic | next oldest topic

Administrative Options: Close Topic | Archive/Move | Delete Topic
Post New Topic  Post A Reply
Hop to:

Contact Us | HUM-MOLGEN

Copyright by HUM-MOLGEN 1995-2015

Powered by: Ultimate Bulletin Board, Version 5.44a
© Infopop Corporation (formerly Madrona Park, Inc.), 1998 - 2000.