news archive genetic news - May 15, 2008

May 15, 2008

your information resource in human molecular genetics

-	Fighting Glioma-Associated Edema Excessive accumulation of fluid in the brain can be prevented by inhibiting glutamate transport to prolong survival.
-	Strength In Numbers A large number of signalling motifs in the receptor complex expressed on the surface of T lymphocytes helps prevent autoimmunity.
-	Generating Human Autoimmune Cells The essential 'ingredients' for producing a type of human immune cell involved in both mucosal immunity and autoimmunity are reported online.
-	Genetic Susceptibility To Obesity Scientists have discovered genetic variants that increase the risk of obesity and insulin resistance in the general population.
-	Stopping DNA Synthesis Before It Starts A small-molecule inhibitor of Cdc7 kinase prevents DNA synthesis and has antitumour activity.
-	Stem-Cell Regeneration Of The Breast Relies On Adhesion Interaction of basal stem cells in the breast with their cellular environment is crucial for their function, and helps towards the regeneration of the mammary glands during pregnancy.
-	Targeting Dormant Leukaemia Cells A new role for a protein involved in leukaemia is described.
-	Insight Into Devastating Pregnancy Condition A paper published online has identified two culprits likely to trigger pre-eclampsia if they are in short supply, opening up the possibilities of early diagnosis and even treatment of the disorder.
-	Starting Out On The Road To Maleness A study of mice now shows how developing gonads start out on the road to maleness.
-	Why We Are All Different A paper takes a close look at the larger DNA variations that influence differences between individual humans and their potential origins and evolutionary history.