news archive May 2003

• Food For Thought: Obesity, Diabetes May Be All In The Head
  Researchers have homed in on a brain mechanism that reduces food intake and affects the availability of blood glucose.
  
• Polymer Scientists Become DNA Detectives
  A report in the June issue may offer a new fast and simple method for identifying SNPs and detecting them in individuals.
  
• Knockout Rats Join Mice In The Lab
  Paper describes the first ever “knockout” lab rats, allowing researchers to study the effect of specific gene defects on rat physiology.
  
• Foxy Duo Make Sugary Signals
  Two molecules, FOXO1 and PGC-1a, interact directly to turn on genes that stimulate insulin-dependent glucose production.
  
• Bone Bonanza
  An Insight in this week's Nature presents a collection of articles that explore key elements of skeletal biology.
  
• Cause Of SARS Confirmed
  The identity of the agent that causes severe acute respiratory syndrome (SARS) has been confirmed.
  
• Young 'Old' Mice Offer Clue To Premature Ageing
  Mice engineered to grow old before their time may help researchers understand premature ageing syndromes.
  

• Antisense RNA Causes Genetic Disease
  Scientists have uncovered a new mechanism for genetic diseases that involves antisense RNA -- an unusual form of RNA that blocks the expression of genes.
  
• Anti-Cancer Drug Duo Delivers One-Two Punch
  A new type of drug decreases the damaging side-effects, and boosts the tumor-busting capacity, of interleukin-2, holding out promise for patients with certain types of cancer.
  
• Understanding Autoimmune Disorders
  Alterations to a key gene may predispose some people to develop autoimmune diseases such as type 1 diabetes.
  
• Anthrax Killer Decoded
  The genome of Bacillus anthracis, the bacterium that causes anthrax, has been sequenced. The results provide an insight into its biology and that of two related nasty relatives, and highlight potential genetic targets for vaccine and drug design.
  
• Hearing Loss
  Rresearchers identify one key gene that seems to be closely linked to progressive hearing loss in mice.
  
• Blood Stem Cell Signalling
  The signalling molecule Wnt may help blood stem cells to divide and self-renew
  

• SARS genome
  SARS genome decoded - free to all on Science Magazine Website
  

• In utero Surgical Technique for Spina Bifida
  NICHD Study To Test Surgical Technique to Repair Spinal Defect Before Birth
  
• Early Diagnosis of Usher Syndrome Type 1 Made Possible by New Findings
  Can Help Ashkenazi Jewish Children Who are Born Deaf and Have Progressive Loss of Sight
  
• Unique Source of Postnatal Stem Cells
  Baby teeth that fall out around a child's sixth birthday contain a rich supply of stem cells
  
• Ovarian Cancer Cells Can Alter Surroundings to Promote Self-Preservation
  Collagen VI appears to help ovarian cancer cells alter their microenvironment so they are more resistant to chemotherapeutic drugs
  
• Sloppy Repair Helps Tuberculosis Bug Resist Drugs
  Shoddy work by a DNA-repair enzyme allows tuberculosis-causing bacteria to develop antibiotic resistance
  
• Anthrax Genome Decoded
  The complete sequence of the 5.2 million base pairs of the DNA in B. anthracis' single chromosome is published
  
• Gene Discovery Opens Door to Further Research In Inherited Neurological Disorders
  Charcot-Marie-Tooth and Distal Spinal Muscular Atrophy Gene May Shed Light on Carpel Tunnel Syndrome and Lou Gehrig's Disease
  

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