news archive April 2010

• Variants Associated with Pediatric Allergic Disorder
  Genetic variants at chromosome 5q22 are associated with pediatric eosinophilic esophagitis (EoE) - a type of allergic disorder often triggered by food allergies.
  
• Mutations in PHF6 Found in T-Cell Leukemia
  The X chromosome gene PHF6 is frequently mutated in a certain type of leukemia
  
• Genetic Risk Variant for Urinary Bladder Cancer
  Another genetic variant associated with risk of urinary bladder cancer is reported in a study
  
• Antibody Has Therapeutic Effect on Mice with ALS
  A biological treatment targeting the protein CD40L has a therapeutic effect on mice with amyotrophic lateral sclerosis (ALS).
  
• Regulating P53 Activity in Cancer Cells
  The protein BRD7 activates p53 and could therefore suppress the development of cancerous tumours.
  
• Anti-RNA Therapy Counters Breast Cancer Spread
  A new type of therapy that prevents the metastatic spread of breast cancer in a mouse model of breast cancer is presented
  
• Mitochondrial DNA Diversity
  A study of normal and cancerous human cells shows that Mitochondrial DNA is more heterogeneous than was thought.
  
• The Power of RNA Sequencing
  RNA sequencing is a powerful tool for teasing apart the genetic mechanisms that underpin variation in gene expression.
  
• ‘Pro-Ageing' Therapy for Cancer?
  The discovery of a signalling pathway that forces cancerous cells to age could aid the development of a general approach for cancer therapy.
  
• Niche Genetics Influence Leukaemia
  Certain blood cancers can be triggered by genetic changes in the blood cells' microenvironment.
  
• Molecular Biology: Clinical Promise for RNA Interference
  The first proof-of-principle study showing that the gene-silencing technique RNA interference (RNAi) can indeed lower levels of gene expression in humans is revealed.
  
• Chemoprevention Cocktail for Colon Cancer
  Treating premalignant colorectal cells with a protein cocktail that 'persuades' them to commit cell suicide may prove a useful method of cancer chemoprevention.
  

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.