posted 12-08-2005 11:19 PM            

SUBJECT: GeneMarker and Ybase

Fellow satelliters,

SoftGenetics has an excellent substitute for
the ABI GeneMapper product. You can download a copy of GeneMarker and try it here:
http://www.softgenetics.com/gm/index.htm

Another very interesting facility has appeared for those interested in differentiating human populations
from each other. It is a microsat. resource based on Y-chromosome markers. You can study their input format and connect names to chromosomes.
View it here:
http://www.ybase.org

and here:
http://www.ybase.org/shaplo.asp

Happy PCRing!

Bert

The Short Tandem Repeat Polymorphism listserv (STRP-L) at NIH is devoted to technical discussions of locating, detecting, multiplexing, binning, and analyzing this type of genetic variant. STRs are valuable in forensic applications, as well as population history reconstructions, coalescence studies, calibrating molecular clocks, setting phase, and providing location markers for TdT and other association and linkage studies.

In and of themselves, they are also markers of carrier status and causes of several triplet repeat polymorphism diseases.

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