We have recently obtained a research grant for a two year post-doctoral position, full-time, dedicated to the study of connexin26-associated skin disease.

Connexin26 is a gap junction protein. In the epidermis and many other tissues, gap junctions form intercellular channels that play an important role in epidermal growth and differentiation.

You will be working in an ambitious multidisciplinary group to investigate how mutations in connexin26 cause skin disease. From previous work we know that several mutations in connexin26 cause very diverse skin phenotypes, sometimes correlated with protein transport defects. The present project will explore various novel mechanisms of gap junction-associated disorders. The successful candidate is expected to participate in the acquisition of more grants to ensure continuation of the post-doc position.

Your profile

You have a PhD (medical) biology or a related field, with an interest in molecular cell biology. Experience with fluorescence and confocal microscopy, RNA interference, cloning and cell culture is essential; prior experience with connexin work is desirable. You are creative, technically skilled, ambitious, motivated and have good communicative skills.

 The department

The department of dermatology of the Maastricht University Medical Center is a leading centre in the study of inherited skin disorders and the molecular genetics of skin diseases. We have a modern, well-equipped laboratory for molecular cell biology where all modern techniques are used, including advanced microscopy applications. With a young and enthusiastic team, we are working at the cutting edge of skin biology.

We offer

Open from: January 2010
Type of employment: Full Time