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Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory
April 17-28, 2009
This intensive one-week discussion course offers successful applicants a unique opportunity to learn the latest concepts and methodologies associated with the study of human neurological disorders such as Alzheimer’s, Parkinson’s and epilepsy. Participants will discuss in detail the strengths and weaknesses of the accumulated experimental evidence underlying our current understanding of these diseases. Fundamental questions - such as how and why particular neurons die in certain disorders - will be discussed in the context of identifying the best experimental approaches to finding answers, whether through the use of transgenic and/or lesion-induced mouse models, functional brain and/or cellular imaging, gain/loss-of function molecular and viral approaches, cellular transplantation, or a combination of these approaches. The course will examine why many of these disorders share apparently common features protein aggregation, specific vulnerability of certain classes of neuron, long incubation period and will discuss to what extent these features reflect common pathological mechanisms. The course will further explore how the underlying mechanisms in these disparate disorders may be targeted for potential diagnostic and therapeutic gain. Extended seminars and discussion by a wide range of leading investigators will further illuminate developments in this rapidly moving field. Participation in the course will provide an essential conceptual and methodological framework for anyone intending to pursue rigorous research.
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Organized by:
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Instructors: Mark Cookson, National Institute on Aging/NIH; Beverly Davidson, University of Iowa College of Medicine; Harry Orr, University of Minnesota |
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Invited Speakers:
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To be announced
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Deadline for Abstracts:
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Application Deadline March 15
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Registration:
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Online Application Information
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E-mail:
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meetings@cshl.edu
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