Modeling Stroke With Increased Precision Scientists have found a way to model different types of stroke with unprecedented precision by targeting individual rat blood vessels with controlled laser bursts.
Fighting Legionnaires' Disease New research indicates how the immune system fights bacteria causing the severe pneumonia Legionnaires' disease.
HIV Nef Damages Antibody Responses Report of a new mechanism by which human immunodeficiency virus (HIV) cripples immune responses in virus-infected AIDS patients.
Genetics Of Earwax Determination Research presents evidence of the genetic basis that determines whether human earwax (cerumen) is wet or dry.
Stopping The Spiral Research findings have important implications for designing new proteins with improved properties, perhaps using left-handed amino acids.
Emerging diabetes drugs in early development The complexity of glucose metabolism and the number of cellular processes affected by diabetes provides ample space for new drug targets and for first-in-class molecules.
2006-01-27
RNA eye: A new player in anti-neovascular therapy The knockdown of VEGFR-1 with a modified siRNA shows remarkable efficacy in two mouse models of retinal angiogenesis associated with macular degeneration or diabetic retinopathy.
2006-01-25
Chimp/Human Antibodies Can Protect Against Smallpox Hybrid laboratory antibodies derived from chimpanzees and humans may provide a potentially safe and effective way to treat the serious complications that can occur following smallpox vaccination
Retinopathy: Ribozymes, Receptors and Really tight junctions Increased blood sugar leads to vascular permeability, increased VEGF pathway expression and induction of angiogenesis. New research pinpoints the main players in this process and highlights therapeutic avenues for intervention.
Brain Cholesterol Metabolism And Alzheimer’s Disease Regulating cholesterol levels in the brain decreases levels of the Amyloid-beta peptide which is thought to be the causative agent involved in the pathology of Alzheimer's disease.
Grammar For Proteins Grammatical rules can be applied to describe the functions of proteins.
Novel Mutation Could Improve Response To Therapy Scientists report a novel mutation in the epidermal growth factor receptor (EGFR) gene that could change the way that EGFR targeted therapies are given to patients with non-small-cell lung cancer.
Fighting The Fat The level of a simple substance in a small brain region may act as a crucial signal in the regulation of body weight.
Determining Brain Gender Scientist explain the function of a protein called alpha-fetoprotein (AFP) which binds to and regulates gender-determining estrogen during fetal development.