
Xtalks — The Life Science Community™, Online webinar
2026-10-21
Neurodegenerative clinical trials present unique challenges that extend beyond scientific and operational complexity. Disease progression, caregiver responsibilities, travel burden, complex assessments and patient availability can all influence recruitment, retention and overall clinical trial experience. As the field continues to advance, incorporating the perspectives of patients and caregivers into clinical development is increasingly important to designing studies that are both scientifically rigorous and feasible for the populations they aim to serve. This webinar will explore practical strategies for integrating patient- and caregiver-centered approaches throughout the clinical development process, from protocol development, including opportunities to incorporate advocacy feedback early and align study endpoints and assessments with the realities of living with neurodegenerative disease. The discussion will also examine key barriers to participation and approaches to improving recruitment and retention. The featured speakers will share operational strategies informed by experience across different phase neurogenerative programs, including considerations for site selection and readiness, visit burden, complex assessments and global coordination. As neurodegenerative development increasingly spans international populations, the webinar will address the additional considerations involved in conducting patient-centered studies across borders. Differences in patient engagement expectations, ethical considerations and regulatory requirements can affect how patient and caregiver perspectives are incorporated into clinical research. Ensuring that patient-centered strategies align with global regulatory standards is essential for successful execution. Finally, the webinar will connect patient-centered protocol design with real-world study execution, highlighting lessons learned from programs across different phases. By bringing together clinical, operational and patient-focused perspectives, the discussion will demonstrate how thoughtful trial design and execution can improve the experience for patients and caregivers while supporting the scientific and operational objectives of a clinical trial. Attendees will gain actionable insights into designing and executing neurodegenerative clinical trials that balance scientific rigor, operational feasibility and the needs of patients and caregivers that move beyond the protocol to create a more meaningful clinical trial experience. Register for this webinar to learn how patient and caregiver perspectives can inform the design and execution of neurodegenerative clinical trials.
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