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Using Recombinant Insulin and Trypsin for Safer Vaccine Production

 
  October 17, 2025  
     
 
Xtalks, Online
2025-12-03


The production of cell-based vaccines requires robust, consistent and contamination-free upstream processes to ensure both product safety and manufacturing efficiency. Animal-free reagents have become the gold standard in biomanufacturing, addressing critical needs for enhanced consistency and reduced risk of contamination. This webinar explores the pivotal roles of two key reagents: recombinant insulin and trypsin in optimizing cell-based vaccine production across commonly used cell systems, including Vero cells and HEK293 cells.

Recombinant insulin has demonstrated significant value in vaccine manufacturing by improving cell culture performance, enhancing viral yield and supporting consistent production across diverse vaccine platforms. Testing in Vero and HEK293 cell systems has shown insulin’s ability to boost productivity. Complementing this with high-purity recombinant trypsin addresses critical safety concerns associated with traditional animal-derived trypsin used in virus expansion and activation processes, while also improving virus infectivity and quality. Through a controlled production process that maintains the inactive form until stabilization, this recombinant trypsin delivers consistent high β-trypsin content while eliminating adventitious contamination risks.

The strategic implementation of recombinant insulin and trypsin delivers enhanced safety, improved efficiency and cost-effective vaccine production across key cell systems.

Register for this webinar to learn how recombinant insulin improves viral yield and manufacturing efficiency in vaccine production.

Keywords: Animal-Free, Cell Culture, Cell Therapy Manufacturing, Commercial Manufacturing, Drug Development, Insulin, Quality, Toxicology/Safety, Vaccine, Vaccine Development, Vaccine Manufacturing
 
 
Organized by: Xtalks
Invited Speakers: Sara Bursomanno, PhD, Senior Global Product Manager, Novo Nordisk Pharmatech A/S
Chantale Julien, Global Product Manager, Novo Nordisk Pharmatech A/S
 
Deadline for Abstracts: 2025-12-03
 
Registration: Free Registration
E-mail: tristan@xtalks.com
 
 
   
 
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