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Early Therapeutic Antibody Development: Addressing the Challenges to Expedite a CMC Program

 
  June 24, 2021  
     
 
Xtalks, Online
2021-07-15


The FDA recently approved the 100th monoclonal antibody (mAb) product for commercial use. In the 35 years since the first approval, monoclonal antibody therapies have become main-stream and their production is considered as a routine, platform process. However, a high proportion of candidate therapeutic antibody drugs fail to come through early development and Chemistry, Manufacturing and Control (CMC) without challenges. Despite the obvious similarities between mAbs and the application of novel discovery and engineering techniques, each product is essentially unique with considerable variability of primary amino acid sequences and post translational modifications (PTMs) contributing to significant differences in physiochemical and biological properties.
 
 
Organized by: Xtalks
Invited Speakers:

Simon Keen, Scientific Leader, Abzena

 

Arron Hearn, PhD. Group Leader Protein Engineering, Abzena

 

 
Deadline for Abstracts: -
 
Registration: Click on Xtalks link provided.
E-mail: helpdesk@xtalks.com
 
   
 
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