EuroSciCon, Cineworld: The O2, Peninsula Square, London, SE10 0DX, United Kingdom
Monday, 20 October 2014 09:00 - Wednesday, 22 October 2014 17:00
OVERVIEW A three day event discussing aspects of vaccine development and vaccinations.
This year there are three main topics for discussion - Next Generation Vaccines: Adjuvants and delivery systems
- Advances in overcoming co-infections
- The use of pseudotypes to study viruses, virus sero-epidemiology and vaccination
With plenty of opportunity for networking and debate, this informal international meeting will bring you up to date with current research and thinking regarding vaccines and vaccination.
This event has an open poster session. Posters can be submitted on any subject related to vaccines and vaccination
PROGRAM OUTLINE Day 1: Next Generation Vaccines: Adjuvants and delivery systems
This session will discuss current research into the development of new or enhanced adjuvants and novel delivery systems which are widely accepted as key to creating more efficacious vaccines with improved methods for storage and delivery. Session Chair: To be confirmed- Morning Poster Session: Vaccine Adjuvants
- Afternoon Poster Session: Vaccine Delivery Systems
Day 2: Advances in overcoming co-infections
The advent of effective combination antiretroviral therapy has made living with, rather than dying from HIV-1 infection a reality. Now, an ageing HIV-1 seropositive population are living with co-infection by pathogens for which effective treatments remain in development. As the effort to develop prophylactic or therapeutic vaccines continue, the aim of this session will highlight advances in the science of pathogens commonly found as co-infections in people living with HIV. Session Chair: Christopher JK Ward, Innate Immune Sensors Group Institute of Infection & Immunity Cardiff University School of Medicine -
- Morning Poster Session: Research in overcoming co -infections
- Afternoon Poster Session: Open poster session.
Day 3: The use of pseudotypes to study viruses, virus sero-epidemiology and vaccination The switching of surface envelope proteins expressed on the surface of pseudotype viruses enables them to be used as surrogate viruses in neutralization/antiviral screening assays and for the study of cell–virus receptor interactions. This day will discuss ongoing research, assay development and applications of the using pseudotype viruses for virus detection and vaccination.
Morning Session
Afternoon Session Animal virus pseudotypes. Chair: Dr Simon Scott, University of Kent, UK
- Morning Poster Session: Human virus pseudotype
- Afternoon Poster Session: Animal virus pseudotypes.
Talks Include: The Next Generation of Vaccines, Adjuvants, and Delivery Systems: Lessons from the Past 50 Years Dr Lawrence Dean Frenkel, Professor, Departments of Pediatrics and Microbiology, University of Illinois, USA
The state of HIV-1 co-infection The introductory talk will briefly outline current understanding of major HIV-1 co-infections. Mr Christopher Ward, PhD Student,Innate Immune Sensors Group, Institute of Infection & Immunity, Cardiff University School of Medicine, University Hospital of Wales
Optimizing delivery of next generation immune potentiators Dr Manmohan Singh, Novartis Vaccines, North Carolina, USA
DNA Vaccination Encoding CD40 Targeted to Dendritic Cells Protects Against Chronic Kidney Disease. Dr Yuan Min Wang, Senior Scientist, Senior Lecturer, University of Sydney Renal Laboratory, Centre for Kidney Research, Australia Tubular immunostimulating complex based on glycolipid and saponin from marine hydrobiont Professor Nina Sanina, Far Eastern Federal University, Russia
Talk title to be confirmed Dr Diego Serraino, MD, Epidemiology and Biostatistics Unit - National Cancer Institute, Italy
Talk title to be confirmed Dr Isabelle Heard, Pasteur Institute, Hopital Pitie-Salpetrière, France
Talk title to be confirmed Dr Sanjay Bhagani, Consultant Physician and honorary Senior Lecturer, Royal Free London Foundation Trust, UK
Talk to be confirmed Professor Nikolai Petrovsky, Flinders Medical Centre, Adelaide Australia
Talk to be confirmed Professor Yvonne Perrie, Aston University, Birmingham, UK
Talk to be confirmed Professor Talin Barisani-Asenbauer, Scientific Director, OCUVAC - Centre of Ocular Inflammation and Infection, Medical University of Vienna, Austria
This will be a paperless meeting, please print out the agenda and abstract book before you come or download the pdf onto your computer or smartphone. The agenda can be found here Keywords: Edible vaccines, microneedles, microparticulates, needle-free delivery, TLRs, vaccine delivery systems, vaccine,therapeutic, vaccines, adjuvant, DNA vaccination, DEC205, CD40, Active Heymann Nephritis (HN), adjuvant delivery system, subunit vaccines, protein conformation and immunogenicity, glycolipids, Anti-vaccine forces, vaccine safety, vaccine effectiveness, public policy, co-infections, HIV, antiretroviral,HIV-1,therapeutic vaccines,therapeutic, vaccines, co-infections, HIV, antiretroviral,HIV-1,therapeutic vaccines,therapeutic, vaccines, Retroviral pseudotype, virus serology, neutralization assays, pandemic preparedness, virus tropism,zoonotic emerging viruses, serological assays,Rabies virus, lyssaviruses, pseudotypes, vaccines, antivirals, sheep, retrovirus, jaagsiekte, ruminant, serology, Feline, retrovirus, rabies, FIV, FeLV, HIV, Retrovirus, Antiretrovirals, susceptiblity, resistance, sheep retrovirus jaagsiekte ruminant serology, Influenza, pseudotypes, pandemic preparedness, sero-surveillance, neutralizing antibodies, influenza, equine, endoprotease, neutralization, SRH
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Invited Speakers:
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About the Speakers
Nigel Temperton obtained his BSc in Microbiology and Genetics from UCL in 1990 and an MSc in Applied Molecular Biology of Infectious Diseases (1992), PhD in Molecular Parasitology (1999) and DLSHTM (2000) from LSHTM. After his PhD, Nigel returned to UCL as a post-doctoral scientist at the Centre for Virology. In 2003 Nigel transferred to the MRC/UCL Centre for Medical Molecular Virology initially as a senior post-doctoral scientist and subsequently Principal Investigator, funded by the MRC and industry. He is currently a Senior Lecturer at the Medway School of Pharmacy and Principal Scientist at the Viral Pseudotype Unit.
Chris Ward BSc is based in the eminent Triantafilou lab at Cardiff University. He has reported on Early Phase advances in HIV-1 immunotherapeutics as well as pattern recogition and host immune evasion themes. His PhD thesis concerns the innate immune recognition of HIV-1 and hepatotropic viruses. Chris sits on the scientific & clinical trial monitoring advisory board of the largest pan-European and Central Asian HIV, HCV and TB patient advocacy group, which advises major pharmaceutical companies concerning clinical trial protocol for compounds used in mono- and co-infected patients.This involvement has nurtured a special academic interest in the immunology of HIV/HCV co-infection.
Yuan Min Wang is currently working at the Centre for Kidney Research as a Senior Scientist and a Senior Lecturer in the University of Sydney, Australia. Dr Wang worked as a Gastroenterologist in China since 1987, obtained her Master’s Degree in the National University of Singapore in 1997. She completed a PhD at University of Sydney in 2002. For the last ten years, Yuan Min has led a program of research in DNA vaccination, regulatory T cells in renal disease. Her high quality research work has been demonstrated by leading journal publications in nephrology and in national and international conference presentation.
Nina Sanina graduated Voronezh State University in 1975 (specialty Biophysics). She works at Far Eastern Federal University since 1978. In 1989, she defended PhD Thesis ‘Thermotropic behavior of the major membrane lipids of marine invertebrates’ (specialty Biochemistry). Since this year, she worked as a Senior Lecturer and then as Associate Professor. In 2006, she defended Dr. Sci Thesis ‘Membrane-forming lipids: physicochemical fundamentals of thermal adaptation of marine invertebrates and macrophytes’ and became Professor. Her main lecture courses are ‘Liquid crystals in biological systems’, ‘Immunology’, ‘Biochemistry’, ‘Biomembranes’, ‘Nanobiotechnology’. She is the author of more than 150 publications and 5 patents.
Lawrence Frenkel is an academic pediatrician, infectious disease specialist, and immunologist, who has devoted himself to teaching, research, clinical care and advocacy for over four decades. He received his MD from Georgetown U, did his residency at the New York Hospital-Cornell, served in the US Public Health Service, assigned to the Clinical Center of the NIH, and did a fellowship at Georgetown in Immunology and Infectious Diseases. He has published or presented over 150 papers (in over 50 countries) fostering his long term interest in international travel and health. Dr. Frenkel has been an editor and reviewer for a score of renowned, peer reviewed publications. He has been an advisor and grant reviewer for the March of Dimes, the World Health Organization, the Pan American Health Organization, the Gates Foundation, the CDC and the NIH, as well as the state health departments of New Jersey and Illinois. He is currently a member of the NJ State Department of Health Immunization Registry Steering Committee and serving his second term as Co-Chair of the New Jersey Immunization Network.
Simon Scott began his research career as a DNA virologist, working in Cambridge and Newmarket on the molecular biology of animal herpesviruses. Following an EU fellowship in Amsterdam studying human papillomavirus oncology, he spent over a decade undertaking research in field of cancer gene therapy using DNA and RNA virus delivery vectors, in both the UK and USA. After joining the University of Kent he established the Viral Pseudotype Unit with Dr Nigel Temperton. The focus of his pseudotype worksince has been on neglected influenza viruses and more recently emerging RNA viruses from other virus families (e.g. flaviviruses, bunyaviruses).
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