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EuroSciCon, Cineworld: The O2, Peninsula Square, London, SE10 0DX, United Kingdom
Tuesday, 01 April 2014 09:00 - Thursday, 03 April 2014 17:00
Obesity, is widely recognized as the largest and fastest growing public health problem in the developed and developing world.
This three day event will discuss aspects of obesity development and treatment in n informal academic setting
This year there are three main topics for discussion
- Predicting obesity for the development of diagnosis and management
- Gene-environment interactions in obesity
- Anti-Obesity Drug Discovery and Development
With plenty of opportunity for networking and debate, this informal international meeting will bring you up to date with current research and thinking regarding obesity.
This event has CPD accreditation
Program Outline
Day 1: Predicting obesity for the development of diagnosis and management
Discovery of predictive markers to assess individual risk of developing obesity will be discussed in an informal setting with plenty of opportunity for networking and debate. Session Chair: To be confirmed - Morning Poster Session: Predicting obesity for the development of diagnosis and management
- Afternoon Poster Session: Open Poster Session
Day 2: Gene-environment interactions in obesity
It has become clear that there are large individual differences in the responsiveness to well-defined energy balance manipulations to control obesity. Overfeeding as well as negative energy balance protocols indicate that the response to standardized experimental treatments is strongly influenced by genetic background. However, testing gene-environment interaction is a relatively new field. This session will discuss identifying the genetic and environmental risk factors (lifestyle and diet) for obesity and the evidence for gene-environment interaction will be examined. Session Chair: Dr Clare Llewellyn, Lecturer in Behavioural Obesity Research, University College London and King's College London, UK Day 3: Anti-Obesity Drug Discovery and Development Obesity, is widely recognised as the largest and fastest growing public health problem in the developed and developing world. Although prevention through education and changes to the obesogenic environment are long-term goals, treatment is required for those who are already obese. Surprisingly, however, treatment options remain quite limited. The main treatment modalities for overweight and obese individuals remain dieting and physical exercise. However some patients find that diet and exercise is not a viable option; for these patients, anti-obesity drugs can be a better alternative than surgery. The pharmacological management of obesity is therefore an exciting option. New treatments are essentially on the horizon, and novel research strategies have very recently come to the fore. This session will discuss the development of therapeutic agents that may reduce body weight by decreasing the consumption or absorption of food, and/or by increasing energy expenditure.
Session Chair: To be confirmed
Talks Include: - Gene-environment interactions in the triangular relationship between obesity, depression and cardiovascular disease, Dr Lucy F. Faulconbridge, Assistant Professor of Psychology in Psychiatry, University of Pennsylvania, USA
- Obesity and metabolic health status: predictive gene signatures, Dr Janice E. Drew, Senior Research Fellow, University of Aberdeen, UK
- Antipsychotics induced obesity: Direct actions on the adipocytes, Professor Nira Ben-Jonathan, Professor of Cancer and Cell Biology, University of Cincinnati, United States
- Thiol redox state as a novel pharmacologic target for obesity, Dr Amany Elshorbagy, Visting Postdoctoral Research Fellow, Lecturer in Medical Physiology, University of Oxford, UK Universityi of Alexandria, Egypt
- Biomarkers of Intake, Professor Jack Winkler, London Metropolitan University, UK
- Different expression of certain adipokines in subcutaneous and visceral tissues between obese and non-obese subjects and their correlations with clinical parameters and periphera metabolic factors., Dr Chantacha Sitticharoon, Department of Physilogy, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
- Obesity, leptin and respiratory control, Dr Mirian Bassi, Post-Doctoral,School of Dentistry, São Paulo State University (UNESP), Araraquara, Sao Paulo-Brazil
- Eating, Epigenetics and Ageing Well: Nature or Nurture: Findings from the Belfast Elderly Longitudinal Free Living Ageing STudy (BELFAST)., Dr Irene Maeve Rea, Senior Lecturer and Consultant Physician Geriatric Medicine, Queens University Belfast and Belfast Health and Social Care Trust, Northern Ireland
- Genetic and Environmental Determinants of Comorbid Obesity in Major Psychiatric Disorders, Dr Margarita Rivera, Lecturer in Psychiatric Genetics, Institute of Psychiatry, King's College London, UK
- Galanin-like peptide (GALP) have anti-obesity effect via the activation of hepatic lipid metabolism, Dr Satoshi Hirako, Post-doctoral fellow, Dept of Anatomy, Showa University School of Medicine, Tokyo, Japan
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Organized by:
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Euroscicon |
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Invited Speakers:
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About the Speakers
Shahrad Taheri is Senior Lecturer in medicine, diabetes and endocrinology at the University of Birmingham. He is also a consultant physician at the Heart of England NHS Foundation Trust where he is lead for weight management and bariatric services (the largest NHS service) and co-director of the Heartlands Biomedical Research Centre (HBMRC). He also has a lead role within the clinical research network (CLRN) and the Birmingham and Black Country NIHR CLAHRC (implementation of effective community care for diabetes; Theme 8).
Satoshi Hirako is a Post-doctoral fellow, Showa University, Tokyo, Japan, Present-2012 and obtained a Ph.D. in Pharmacy, josai University, Saitama Japan, March 2012 . He also has a Master of Medical Nutritional Science in Pharmacy, Josai University, Saitama Japan, March 2009.
Douglas MacNeil received his Ph. D. from the University of Wisconsin before joining Merck. He has extensive experience in drug discovery in Metabolic Disorders, including expertise in target identification, target validation, project initiation, and discovery team leadership. He initiated seven programs that successfully delivered compounds for development; four of these achieved clinical proof of concept. He has also developed collaborative projects with international partners in Japan, India, China, Germany, and Denmark. He has extensive expertise in G-protein coupled receptors, energy homeostasis and metabolic diseases, resulting in over 90 publications and 15 US patents.
Nira Ben-Jonathan, Ph.D, is Professor of Cancer and Cell Biology, University of Cincinnati, Ohio, USA. She published 160 manuscripts, edited one book, and contributed 12 chapters to textbooks and encyclopedias. The focus of her research is on the regulation of pituitary functions, breast cancer and human obesity. She mentored 65 students and scientists, served on journal editorial boards and scientific committees, and has been a member and chairman on NIH, DOD and Komen study sections. She was elected Fellow of the AAAS and Chairman of the Gordon Research Conference, and received the Rieveschl Award for Outstanding Research.
Clare Llewellyn had an initial career working on the commercial side of the pharmaceutical industry, before she retrained as a psychologist, completing an MSc in Health Psychology, then a PhD focusing on genetic influences on appetite and growth, both at University College London (UCL). She is currently a Lecturer in Behavioural Obesity Research at the Health Behavioural Research Centre, UCL. The main focus of her work is to understand why some individuals gain weight, but others remain effortlessly lean, in response to the current ‘obesogenic’ environment. Given that body weight is highly heritable, researchers have been tasked with marrying up the seeming paradox of both genetic and environmental determination of weight. The hypothesis that Clare has been developing is that ‘obesity genes’ influence weight through their effects on appetite, thereby providing a platform for gene-environment interaction – individuals who inherit a more avid appetite are susceptible to overeating in an environment with an abundant food supply, and at risk of excessive weight gain.
Janice Drew is a Senior Research Fellow at the University of Aberdeen. She received her molecular biology Ph.D. in 1994 (University of Durham, UK). Following postodoctoral training in molecular neuroendocrinology at the Rowett Research Institute (Aberdeen, UK), she led a Scottish Government programme, diet, obesity and cancer. Since merger with University of Aberdeen (2008) she has focused on molecular and cellular effects of obesity, its impact on cell defence systems, impaired metabolic health and cancer risk. She has developed a new MSc Molecular Nutrition programme and quest edited special issue Obesity Cancer Links (The Open Obesity Journal, 2:10-94, 2010).
Amany Elshorbagy graduated from Alexandria Faculty of Medicine, Egypt, and received her PhD from the University of Oxford in 2010. During PhD work she combined medical background with epidemiologic tools to derive novel biological concepts from several large Eurpopean and Hispanic datasets, supported by dietary and drug studies in rodents The result of this work was to highlight the role of amino acids, in particular sulfur amino acids, in regulation of fat mass in humans, and their potential usefulness as an anti-obesity drug target.
Chantacha Sitticharoon graduated from Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand in 2001 with honours. She completed her PhD degree in Physiology from Faculty of Medicine, Nursing and Health Sciences, Monash University Australia in 2009. Her PhD thesis was about expressions of appetite regulating peptides in sheep hypothalamus in various conditions. Now, She has been working as an instructor at Department of Physilogy, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand since 2001. Her reseach interests include obesity, appetite regulation, and regulation of reproduction, especially factors involved in early onset of puberty.
I Maeve Rea, Senior Lecturer/Consultant Physician in Geriatric Medicine at Queens University Belfast, was educated at Queens University and did postgraduate research in immune-genetics at Stanford University with Prof Rose Payne. She teaches widely in the Undergraduate Medical curriculum and within her Health Service remit, she provides a clinical service to Elderly people, with a special interest in patients over 90 years of age. Dr I Maeve Rea has a long-time research interest is in healthy ageing and set up and co-ordinates a longitudinal study of octo/nonagenarians, Belfast Elderly Longitudinal Free-living Ageing STudy (BELFAST) and is a Prinicpal Investigator in the Genetics of Healthy Ageing Study (GeHA), which is contributing to understanding the genetic, immunological, cardiovascular and nutritional factors contributing to good quality ageing.
Margarita Rivera is a BRC Senior Postdoctoral Researcher at the MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry. Her work focuses on investigating the genetic relationship between major psychiatric disorders, mainly depression and bipolar disorder, and obesity-related diseases (i.e. type 2 diabetes, metabolic syndrome, cardiovascular disorders, etc). The goal of her research is to get a better understanding of the molecular genetic basis of comorbidity between psychiatric disorders and obesity-related diseases, both of which have major public health, clinical, economic, personal and social implications worldwide.
Mirian Bassi: Physiotherapist, Specialist in Pulmonary Rehabilitation (2002); Master degree (2004) and Ph.D. (2008) in Physiological Sciences at Medical School of São Paulo University, Ribeirão Preto- Brazil; Post-doctoral training in cardiovascular physiology at Guyton Research Center, University ofMississippi Medical Center, USA (2009) in collaboration with Dr. John E. Hall; Visiting Research at Department of Physiology and Neurobiology, University of Connecticut, USA (2012) in collaboration with Dr. Daniel Mulkey, studding the central role of leptin on neuronal activity of respiratory neurons (electrophysiology). Currentily is is post-doc fellow at the Department of Physiology and Pathology, School of Dentistry - São Paulo State University, Brazil studing participation of leptin on cardiorespiratory control mechanisms. Additional Confirmed Speakers Include - Professor Gertjan Van Dijk, Center for Behavior and Neurosciences, University of Groningen, The Netherlands
- Dr L. Joseph Su, National Institutes of Health, National Cancer Institute, USA
- Dr Shahrad Taheri ,Senior Lecturer in Endocrinology, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, UK
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Deadline for Abstracts:
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Feb 10th 2014
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Registration:
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https://www.regonline.co.uk/Register/Checkin.aspx?EventId=1444289
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E-mail:
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astrid.englezou@euroscicon.com
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