Abcam, Online
2014-02-05
Topics: - Introduction to the molecular organisation and regulation of glutamate receptors (GluRs), discussion of special challenges - Choice of antigens for anti-GluR antibody preparation; their advantages and limitations - Overview some of the immunochemical approaches used for the investigation of GluRs - Validation of antibodies and required controls for various immunochemical techniques - Discussion of common problems and pitfalls in execution of these techniques or interpretation of the data
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Invited Speakers:
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Elek Molnár, MD, PhD, FHEAElek Molnár graduated in General Medicine (MD) from the Albert Szent-Györgyi University, Szeged, Hungary in 1986 and remained there as a Research Fellow in Biochemistry. He moved in 1989 to the State University of New York, Syracuse, USA where he carried out research for his PhD. In 1991 Elek joined the Medical Research Council (MRC) Anatomical Neuropharmacology Unit, University of Oxford, UK where he started his studies of glutamate receptors (GluRs). In 1997 he was appointed as Lecturer in Pharmacology at the University of Newcastle upon Tyne, UK. In 1999 Elek joined the MRC Centre for Synaptic Plasticity, University of Bristol, UK and in 2004 he was appointed as Professor of Neuroscience. He studied the developmental and activity dependent changes in the molecular organization, signaling and function of GluRs. Elek used a combination of molecular, pharmacological, immunochemical and imaging approaches to gain understanding of the roles of GluRs in the central nervous system.
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