Euroscicon, Cineworld: The O2, Peninsula Square, London, UK
Tuesday, 26 November 2013
9:00 – 9:45 Registration
9:45 – 10:00 Introduction by the Chair: Professor. Chris Lowe, Department of Chemical Engineering and Biotechnology, University of Cambridge, UK
10:00 – 10:30 Talk title to be confirmed Dr Martina Micheletti, The Advanced Centre for Biochemical Engineering, University College London, UK
10:30 – 11:00 Confinement phenomenon based bio-process intensification using monolithic microreactors Professor Galip Akay, School of Chemical Engineering and Advanced Materials, Newcastle University Bio-Process intensification, B-PI (by a factor of 5-200 fold compared with batch processing) is achievable using monolithic microreactors with well defined physical and biochemical structure of pores used as support for bacteria or cells. This enhancement is due to 'confinement phenomenon' in which the behaviour of microorganisms is dependent on their confining environment. Recent examples of B-PI pioneered at Newcastle University include fermentation, antibiotics and enzyme production as well as tissue engineering and Agri-Process Intensification through bacterial nitrogen fixation by plants. Mechanism of B-PI will be discussed.
11:00 – 11:30 Speakers’ photo then mid-morning break and poster exhibition and trade show
11:30 – 12:00 Lyophilised Biopharmaceticals- Looking at Cake Properties Dr Daryl R Williams, Director of Development, Discovery Space and Reader in Particle Science, Department of Chemical Engineering, Imperial College An innovative method for the mechanical testing of freeze-dried biopharmaceutical cakes in situ vials has been developed. This simple and quick compression test allows a range of cake mechanical properties to be assessed quantitatively. It can be readily applied to fragile and moisture sensitive freeze-dried cakes within the vials. Freeze dried mannitol, sucrose and trehalose samples all yielded linear compressive elastic behavior for small strains with Young's Moduli of 25, 120 and 170 kPa respectively. This method discriminates readily between the three excipients reported here and can be used to optimise formulation of biopharmaceutical systems.
12:00 – 12:30 Oral Presentations
12:30 – 13:30 Lunch, poster exhibition and trade show
13:30 – 15:00 Question and Answer Session
15:00 – 15:30 Afternoon Tea, last poster session and trade show 15:30 – 16:00 Talk title to be confirmed Speaker to be confirmed Applikon Biotechnology, UK
16:00 – 16:30 Talk title to be confirmed Speaker to be confirmed m2p-labs
16:30 - 17:00 Chairman’s summing up
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