home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Events -> Meetings and Conferences  
 

B Cells From Bedside To Bench And Back Again

 
  April 30, 2013  
     
 
European Science Foundation, Pultusk
2-7 September 2013


B cells are lymphocytes that play a key role in the immune response.

A principal function of B cells is to differentiate into plasma cells that secrete antibodies against exogenous antigens, and into memory B cells that retain the memory of the encounter against future challenges. However, the advent of B cell depletion therapies, originally developed against B cell malignancies, has revolutionised the way we see the role of the B cell.  Observations from the clinical use of agents such as Rituximab have resulted in the recognition that B cells have extremely important effector and regulatory roles other than antibody provision. If we use this information to increase our understanding of B cell biology we may well be able to take innovative solutions back into the clinic to complete the translational cycle.  The control of B cell development and homeostasis is the result of a very fine balance between production, survival, and proliferation which is impacted by key survival factors. B cells are found in specialized niches that provide such factors.  As our appreciation of the multifunctional nature of the B cell grows, so does the requirement for knowledge of factors affecting the proper control and development of the B cell. 

The tools at our disposal for investigating biomedical issues are becoming ever more sophisticated, with high throughput sequencing enabling many repertoire studies that were otherwise impossible, high resolution imaging of cellular and subcellular compartments facilitating the visualisation of spatial organisation in unprecedented detail, and a genomics revolution that opens our eyes to new concepts such as cell-cell transfer of miRNA, or protein variation due to transcriptional mutation.

In this conference we will bring together eminent clinicians, biologists, mathematicians, biophysicists to discuss the explosion of paradigm-shifting discoveries in B cell biology and their relevance to healthy immunity.

 

2 September 2013: arrival day
3 - 6 September 2013: conference
7 September: departure after breakfast

 
 
Organized by: European Science Foundation
Invited Speakers:
  • Deborah Dunn-Walters, Kings' College London School of Medicine, UK

  • Federico Caligaris-Cappio, University Scientific Institute San Raffaele, IT

  • Nathalie Bonnefoy-Berard, Université de Lyon, FR

  • Ludvig Sollid, University of Oslo, Norway

  • Marc De Buyzere, Ghent University Hospital, BE

  • Antonio Lanzavecchia, Institute for Research in Biomedicine, CH

  • Andrew Chan, Genentech, USA

  • Ramit Mehr, Bar-Ilan University, Israel  

  • Claudia Mauri, University College London, Windeyer Institute, UK

  • Frances Lund, University of Rochester, Rochester, USA

  • Richard Lo-Man, Institut Pasteur, FR

  • Frank Emmert-Streib, Queen's University Belfast, IE

  • Padraic Fallon, Trinity College Dublin, IE

  • Lucia Mincheva-Nilsson, Umeå University, SE

  • Facundo Batista, London Research Institute, Cancer Research UK, UK

  • Rita Carsetti, University of Tor Vergata, IT

  • Jo Spencer, Guy's Hospital, UK

  • Andreas Cerutti, Barcelona Biomedical Research Park, Barcelona, ES

  • Irit Sagi, The Weizmann Institute of Science,Israel

  • Stephane Mancini, Faculté des Sciences de Luminy, FR

  • Deborah Dunn-Walters, Guy's Hospital, UK

  • Ken Duffy, Hamilton Institute, Ireland

  • Idit Shachar, The Weizmann Institute of Science, Israel

  • Claudia Berek, DRFZ, DE

  • Mikael Karlsson, Karolinska Institutet, SE

  • Pamela Schwartzberg, National human genome research institute, USA

 
Deadline for Abstracts: 3 June 2013
 
Registration:

Application is officially open.  To apply please click here

Application deadline: 3 June 2013

For any query, please contact the Conference Officer.
E-mail: conferences@esf.org
 
   
 
home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
 
 

Generated by meetings and positions 5.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995- HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.