Kellogg Conference Hotel at Gallaudet University , Washington, DC, USA
Oct 28 2011 8:30AM - 5:00PM
Review and evaluation of predictive performance of human pharmacokinetics models using a large cross-company database of diverse compound properties. The prediction of human pharmacokinetics based on in vivo, in vitro and physicochemical properties has made signifi cant contribution to the rate of success in advancing new medicines from discovery to the clinic. However, there is still no industry consensus nor regulatory accepted best practices for predicting human pharmacokinetics. This workshop will bring together key stakeholders, including regulators, industry scientists, academia, and leading experts to: • Share the results of this unprecedented PhRMA initiative • Present case examples of the impacts of prediction eff orts on candidate selection, dose determination, drug interaction or toxicity risk assessment or clinical planning • Discuss best practices and issues or challenges to reaching consensus on predictive eff orts associated with experimental design and data quality Event Code: 11034
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