Genomic and Proteomic Approaches to Complex Heart, Lung, Blood, & Sleep Disorders

This highly acclaimed course covers the application of statistics, molecular biology and genetics to the analysis of complex diseases such as asthma, hypertension and coronary heart disease. Both human and animal model data are presented and considered in depth.

Students learn to detect the genetic basis of disease, perform linkage analysis, conduct genome scans, analyze quantitative trait loci, detect gene interactions, map complex disease genes and clone genes. Emphasis is also placed on how to characterize gene function using the latest in biochemical and molecular genetic techniques. Contemporary approaches to gene discovery such as mutagenesis, microarray analysis, comparative genomics and SNP discovery and analysis are also covered. Social and ethical issues surrounding the generation and use of genetic information are discussed during the course.

Intensive hands-on workshops further expose students to the bioinformatics tools such as: Omim, MGD, Unigene, GeneBank, Blast, Gene-scan, SwissProt and Entrez.

The formal lectures, discussion groups, demonstrations and tutorials, study sessions, recreational activities and informal residential interaction provide a unique and varied learning opportunity. The course is limited to 35-40 students to provide informal and meaningful interaction with the entire group.

2010 Speakers Include:

Terri Beaty, Ph.D., Johns Hopkins University
Eugene Bleecker, M.D., Wake Forest University
Molly Bogue, Ph.D., The Jackson Laboratory
Carol Bult, Ph.D., The Jackson Laboratory
Elissa Chesler, Ph.D., The Jackson Laboratory
Gary Churchill, Ph.D., The Jackson Laboratory
Nancy Cox, Ph.D., University of Chicago
Jeff Drazen, M.D., Harvard Medical School, New England Journal of Medicine
Andrew Greene, Ph.D., Medical College of Wisconsin
Ross Hardison, Ph.D, Pennsylvania State University
Gregory Hawkins, Ph.D., Wake Forest University
Joachim Herz, M.D., UT Southwestern
Naftali Kaminski, M.D., University of Pittsburgh Medical Center
Benjamin King, B.S., The Mount Desert Island Biological Laboratory 
Ron Korstanje, Ph.D., The Jackson Laboratory 
Donna Maglott, Ph.D., National Center for Biotechnology Information, NIH
Deborah Meyers, Ph.D., Wake Forest University 
Allan Pack, Ph.D., University of Pennsylvania
Beverly Paigen, Ph.D., The Jackson Laboratoryl
Barry Paw, M.D., Ph.D., Harvard Medical School/Brigham & Women's Hospital
Luanne Peters, Ph.D., The Jackson Laboratory 
Karen Svenson, B.A., The Jackson Laboratory
Donata Vercelli, M.D., University of Arizona, Arizona Respiratory Center
Erika von Mutius, M.D., MSc, Munich University Children's Hospital
Jill Recla, The Jackson Laboratory
Keith Sheppard, The Jackson Laboratory
Jianfeng Xu, M.D., Ph.D., Wake Forest University

• Registration Fees: $1950.00 Standard registration; $1400.00 Student Registration (requires proof of enrollment in an accredited degree program, or postdoctoral training program, or medical internship)

Registration fee includes course materials, most meals and shared lodging

website: http://courses.jax.org/2011/hlb.html