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Molecular Chaperones & Stress Response

 
  January 27, 2010  
     
 
Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory
May 4 - 8, 2010


The meeting will feature advances in the areas of structure and mechanism of action of molecular chaperones; mechanisms of induction of the stress response; the role of chaperones in protein degradation, and chaperone function in disease, development and organellar homeostasis. Chaperones are intimately involved in basic biological processes such as protein translation, folding, complex assembly and disassembly, translocation across membranes and protein degradation.

The contribution of heat shock proteins, to protein folding in vivo across the entire proteome will be described alongside function of specialized chaperones with more limited clientele. The interactions of chaperones and unfolded and misfolded proteins will be discussed in molecular and atomic detail. At the cellular level, the interactions between chaperones in the formation of protein folding networks will be discussed and at the physiological level the impact of altered chaperone buffering capacity on organeller, cellular and organismal function will be discussed.

The format of the meeting will include morning and evening sessions consisting of 2/3 25 minute talks and between six to eight or short talks per session, selected from the abstracts, principally on unpublished work. In addition, there will be three poster sessions, held in the afternoons. The organizers will decide the suitability of each abstract for oral or poster presentation, but please specify if you prefer a poster.

 

 
 
Organized by: F. Ulrich Hartl, David Ron, Jonathan Weissman
Invited Speakers:

Sessions & Discussion Leaders:
CHAPERONE BIOCHEMISTRY & PROTEIN FOLDING
Chairperson: James Bardwell
Invited speakers: Helen Sabil , Art Horwich (tent.)

CHAPERONE FUNCTION IN DISEASE & DEVELOPMENT
Chairperson: Sue Lindquist
Invited speaker: Elke Duerling

EVOLUTION & REGULATION OF
PROTEIN FOLDING MACHINES

Chairperson: Judith Frydman
Invited speakers: Hanna El-Samad , Vijay Pande

QUALITY CONTROL & PROTEIN TRAFFICKING
Chairperson: Ramanujan Hegde
Invited speaker: Kenji Kohno

CHAPERONES & PROTEOLYSIS
Chairperson: Bob Sauer
Invited speaker: Thomas Langer

DISEASES OF PROTEIN MISFOLDING
Chairperson: Andy Dillin
Invited speaker: David Eisenberg

MANIPULATING CHAPERONE NETWORKS
& PROTEIN FOLDING PATHWAYS

Chairperson: Bill Balch
Invited speaker: Peter Walter

 
Deadline for Abstracts: February 12, 2010
 
Registration:

https://meetings.cshl.edu/meetingR/Default.aspx

E-mail: meetings@cshl.edu
 
   
 
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