BioPark Hertfordshire, Welwyn Garden City
3rd July 2009
8:45 - 9:30 Registration 9:30 - 9:45 Introduction by the Chair: Dr Stephen Thompson, King's College London, UK 9:45 - 10:15 Cytokine detection in collagen-induced arthritis Dr Richard Williams, Kennedy Institute of Rheumatology Division, Imperial College, UK Collagen-induced arthritis is a model of rheumatoid arthritis that has been used extensively to validate novel therapeutic targets. The main pathological features of the disease include synovitis, pannus formation and joint erosion. There is a great deal of interest in the development and testing of drugs with the capacity to modulate inflammatory pathways in arthritis. Hence, there is a need to monitor the effect of novel treatments on cytokine expression in vivo. This presentation will focus on the techniques used to quantify changes in cytokine expression following therapeutic intervention 10:15 - 10:45 Using ELIspot to detect rare antigen specific T cells Dr Tim Tree, Kings College, London 10:45 - 11:15 Dissecting regulatory and effector responses using cytokine secretion assay and artificial antigens Dr John Campell – Miltenyi Biotec Ltd, Surrey, UK 11:15 - 11:25 Speakers photo 11:25 – 12:00 Mid-morning break and poster viewing 12:00 - 12:30 IL-10, regulatory T cells and respiratory health: the role of the vitamin D pathway Dr Catherine Hawrylowicz, Kings College, London 12:30 – 13:00 Application of cytokines assays in the biotechnology sector - from proof-of-principle to clinical trials Dr James N Francis, Senior Vaccine Development Scientist, Immune Targeting Systems Ltd, London, UK 13:00 - 13:10 Introduction to the Biopark 13:10 – 14:00 Lunch and poster viewing 14:45 - 15:45 Troubleshooting Panel Discussion 15:45 - 16:00 Afternoon Tea/Coffee and last poster viewing 16:00 – 16:30 Failing IHC visualization of small proteins Dr Chris van der Loos, the Netherlands 16:30 - 17:00 Differing multiplex cytokine analysis platforms Dr Gendie Lash, Newcastle University, UK 17:00 - 17:30 Chairman's summing up & close. 18:00 Soiree at *The Best Western Homestead Court Hotel for all the participants
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